Evidence map›Paper›PMID 42850403›Full record

ArticleSkeletal radiology2026

CIC-rearranged sarcoma of the arm presenting as a soft tissue mass with regional lymphadenopathy and tumor thrombus.

Manish Saini, Stuti Chandola, Sameer Rastogi, Adarsh Barwad, Shamim Ahmed Shamim, Stanzin Spalkit

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Article in Skeletal radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Manish SainiDepartment of Radiodiagnosis and Interventional Radiology, All India Institute of Medical Sciences, New Delhi, India.
Stuti ChandolaDepartment of Radiodiagnosis and Interventional Radiology, All India Institute of Medical Sciences, New Delhi, India.
Sameer RastogiDepartment of Medical Oncology, All India Institute of Medical Sciences, New Delhi, India.
Adarsh BarwadDepartment of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Shamim Ahmed ShamimDepartment of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
Stanzin SpalkitDepartment of Radiodiagnosis and Interventional Radiology, All India Institute of Medical Sciences, New Delhi, India. stanzn156@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Capicua transcriptional repressor (CIC)-rearranged sarcoma is an aggressive and rare small round cell tumor predominantly affecting the soft tissues of extremities, often with early metastasis and poor prognosis. We report a case of a 46-year-old female presenting with a CIC-rearranged sarcoma of the right arm, notably complicated by extensive tumor thrombus involving the brachial, axillary, and subclavian veins, extending into the internal jugular vein, and regional lymphadenopathy. While tumor thrombus in CIC-rearranged sarcoma has been described in several abdominal cases, this is the first case described in the extremity, to the best of our knowledge. This case highlights the challenges in diagnosing this rare entity, the critical role of molecular confirmation, and the unusual presentation of widespread venous involvement, impacting staging and treatment considerations.

Indexed as

CIC-rearranged sarcomaMagnetic resonance imagingSmall round cell tumorsSoft tissue sarcomasTumor thrombus

Identifiers

PMID42850403

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.