Evidence map›Paper›PMID 42850380›Full record

ArticleAesthetic plastic surgery2026

Modified Sub-Brow Blepharoplasty Reduces Early Postoperative Directional Wrinkles Without Compromising Surgical Outcomes: A Prospective Randomized Controlled Trial.

Chen Huang, Yixin Ren, Xianghao Xu, Sitong Liang, Baoqiang Song, Zhen Liang, Jiao Cao

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Article in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chen Huang *Department of Plastic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.
Yixin Ren *Department of Plastic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.
Xianghao Xu *Department of Plastic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.
Sitong LiangSchool of Nursing, Xi'an Medical College, Xi'an, 710309, China.
Baoqiang SongDepartment of Plastic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China. songbq2012@163.com.
Zhen LiangDepartment of Plastic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China. lianglyzz@163.com.ORCID http://orcid.org/0009-0002-9622-5222
Jiao CaoDepartment of Plastic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China. caojiao1986@163.com.

Funding

Xijing Hospital XJZT25QN28
6 · The paper itself

Abstract

backgroundSub-brow blepharoplasty has become the preferred surgical approach for moderate-to-severe upper eyelid aging. Over the years, numerous modifications and innovations have been introduced to achieve more natural, durable, and precise postoperative outcomes.

objectiveWe conducted a prospective randomized controlled study to demonstrate that our modified sub-brow blepharoplasty technique can achieve a more natural upper eyelid contour in the early postoperative period while maintaining surgical outcomes during the available 6 month follow-up.

methodsBetween June 2024 and June 2025, 60 patients were enrolled and randomly assigned to either the experimental group (modified sub-brow blepharoplasty) or the control group (orbicularis oculi muscle flap crossover fixation blepharoplasty). In addition to preoperative baseline characteristics, postoperative outcomes were evaluated using both subjective and objective measures.

resultsThere were no significant differences between the two groups in sex distribution, mean age, or upper eyelid skin laxity grading at baseline. At 3 months postoperatively, the experimental group showed a significantly lower incidence of abnormal directional wrinkles in the upper eyelid, higher physician GAIS scores, and lower anxiety levels. At 6 months postoperatively, the early between-group differences were no longer observed, no significant differences were observed between the two groups in any subjective or objective outcome measures.

conclusionIn this study, the modified sub-brow blepharoplasty technique provided more natural short-term aesthetic results while maintaining comparable surgical outcomes during the available 6 month follow-up. LEVEL OF EVIDENCE I: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Indexed as

Abnormal directional wrinklesRandomized controlled trialSub-brow blepharoplastyUpper eyelid rejuvenation

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.