Evidence map›Paper›PMID 42850357›Full record

ArticlePediatric research2026

Inflammatory burden and coronary aneurysm risk in Kawasaki disease: appraising the Aggregate Index of Systemic Inflammation.

Khaled Saad, Shimaa Elwardany Aly, Saiel S K Zeid, Ahmad Roshdy Ahmad, Mohamed Shawky Elfarargy, Mohammad Elkossi, Muhammad Husnain Mumtaz, Mohamad-Hani Temsah

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Article in Pediatric research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Khaled SaadDepartment of Pediatrics, Assiut University, Assiut, Egypt. Khaled.ali@med.au.edu.eg.ORCID http://orcid.org/0000-0002-8473-6116
Shimaa Elwardany AlyDepartment of Primary Care Nursing, Faculty of Nursing, Al-Ahliyya Amman University, Amman, Jordan.
Saiel S K ZeidDepartment of Pediatric Cardiology, Bashkir State Medical University, Ufa, Republic of Bashkortostan, Russia.
Ahmad Roshdy AhmadDepartment of Pediatrics, College of Medicine, Jouf University, Sakaka, Saudi Arabia.
Mohamed Shawky ElfarargyDepartment of Pediatrics, College of Medicine, Jouf University, Sakaka, Saudi Arabia.
Mohammad ElkossiStepping Hill Hospital, Stockport, Greater Manchester, UK.
Muhammad Husnain MumtazAllama Iqbal Medical College, Lahore, Pakistan.
Mohamad-Hani TemsahDepartment of Pediatrics, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

impactThe Aggregate Index of Systemic Inflammation (AISI) may serve as an additional inflammatory marker for identifying children with Kawasaki disease (KD) who require closer coronary surveillance. AISI integrates standard hematological parameters and may complement, rather than replace, established clinical and echocardiographic risk assessment. Current evidence supports further prospective validation before AISI can be included in treatment decision pathways. AISI-based risk stratification may contribute to future personalized approaches in KD management.

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.