Evidence map›Paper›PMID 42850328›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2026

Movement of central retinal vessel trunk and its correlation with lamina cribrosa pores movement after short-term intraocular pressure elevation.

Qi Zhang, Min Chen, Kaijun Wang, Ya Xing Wang

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Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Qi ZhangEye Center of Second Affiliated Hospital, School of Medicine, Zhejiang University, No. 1 Xihu Boulevard, Hangzhou, Zhejiang Province, 310009, China.
Min ChenEye Center of Second Affiliated Hospital, School of Medicine, Zhejiang University, No. 1 Xihu Boulevard, Hangzhou, Zhejiang Province, 310009, China.
Kaijun Wang *Eye Center of Second Affiliated Hospital, School of Medicine, Zhejiang University, No. 1 Xihu Boulevard, Hangzhou, Zhejiang Province, 310009, China. ze_wkj@zju.edu.cn.ORCID http://orcid.org/0000-0001-6961-3655
Ya Xing Wang *Beijing Visual Science and Translational Eye Research Institute (BERI), Eye Center of Beijing Tsinghua Changgung Hospital, Tsinghua Medicine, Tsinghua University, 168 Litang Road, Changping District, Beijing, 102218, China. yaxingwang@tsinghua.edu.cn.

Funding

the Key Research and Development Program of Zhejiang Province NO.2025C02154the Medical and Health Science and Technology Plan Project of Zhejiang Province of China No. 2025KY842
6 · The paper itself

Abstract

purposeTo investigate the relationship between central retinal vessel trunk movement and lamina cribrosa pores (LCPs) movement during acute intraocular pressure (IOP) elevation and assess whether vessel trunk movement may serve as a potential indicator of LCPs movement.

methodsDuring a dark room prone provocative test (DRPPT), angle-closure suspects remained prone in a dark room for 2 h. Tonometry, optical coherence tomography, and fundus photography were performed at baseline and within 5 min after DRPPT. Movement distance and direction of the central retinal vein trunk (CRVT), central retinal artery trunk (CRAT), and LCPs were measured.

resultsNinety-four eyes of 56 participants were included. IOP increased from 16.3 ± 3.3 to 23.4 ± 4.3 mmHg. Mean movement distances were 23.3 ± 14.2 μm for CRVT and 21.5 ± 13.9 μm for CRAT. In 38 eyes with identifiable LCPs, mean absolute distance differences between CRVT/LCPs and CRAT/LCPs were 9.1 ± 8.2 and 9.5 ± 8.2 μm, respectively, and mean absolute angular differences were 22.5 ± 18.0° and 22.9 ± 17.5°. CRVT and CRAT movement distances were significantly correlated with LCPs movement distance, while circular-circular analysis showed strong associations between movement directions (both r

conclusionCentral retinal vessel trunk movement was correlated with LCPs movement during acute IOP elevation in eyes with visible LCPs, although individual prediction remained variable.

Indexed as

Central retinal vessel trunkIntraocular pressureLamina cribrosa poresMovement

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.