Evidence map›Paper›PMID 42850325›Full record

ArticleNature microbiology2026

Sickle cell haemoglobin status shapes malaria parasite genotype in asymptomatic infections.

Helena D Hopson, Alejandra Herbert-Mainero, Aline Gaelle Bouopda-Tuedom, Charlène Tina Nanssong-Vomo, Brigitte Tumamo Fotso, Belinda Claire Kiam, Ibrahima Ibrahima, Clément Onguene, Luc Abate, Radoslaw Igor Omelianczyk and 7 more

Abstract read
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In one paragraph

Article in Nature microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Helena D HopsonDepartment of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT, USA.ORCID http://orcid.org/0000-0003-4341-7968
Alejandra Herbert-MaineroDepartment of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT, USA.
Aline Gaelle Bouopda-TuedomMalaria Research Unit, Centre Pasteur du Cameroun, Yaoundé, Cameroon.
Charlène Tina Nanssong-VomoMalaria Research Unit, Centre Pasteur du Cameroun, Yaoundé, Cameroon.
Brigitte Tumamo FotsoMalaria Research Unit, Centre Pasteur du Cameroun, Yaoundé, Cameroon.
Belinda Claire KiamMalaria Research Unit, Centre Pasteur du Cameroun, Yaoundé, Cameroon.ORCID http://orcid.org/0009-0000-8146-1527
Ibrahima IbrahimaMalaria Research Unit, Centre Pasteur du Cameroun, Yaoundé, Cameroon.
Clément OngueneMalaria Research Unit, Centre Pasteur du Cameroun, Yaoundé, Cameroon.
Luc AbateMIVEGEC, Université de Montpellier, IRD, CNRS, Montpellier, France.ORCID http://orcid.org/0000-0003-3973-3036
Radoslaw Igor OmelianczykDepartment of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT, USA.ORCID http://orcid.org/0000-0002-3471-0057
Heather D EvansDepartment of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT, USA.
Lyra E HortonDepartment of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT, USA.
Gavin BandCentre for Human Genetics, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-1710-9024
Tracey J LambDepartment of Pathology, University of Utah School of Medicine, Salt Lake City, UT, USA.ORCID http://orcid.org/0000-0003-0620-3944
Lawrence S AyongMalaria Research Unit, Centre Pasteur du Cameroun, Yaoundé, Cameroon.
Sandrine E NsangoMalaria Research Unit, Centre Pasteur du Cameroun, Yaoundé, Cameroon. nsango@pasteur-yaounde.org.ORCID http://orcid.org/0000-0002-0607-0881
Ellen M LefflerDepartment of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT, USA. leffler@genetics.utah.edu.ORCID http://orcid.org/0000-0002-1614-9366

Funding

American Heart Association (American Heart Association, Inc.) 24POST1200601
6 · The paper itself

Abstract

Sickle cell haemoglobin (HbS) confers protection against symptomatic malaria caused by Plasmodium falciparum. HbS carriers with symptomatic malaria harbour parasites enriched for P. falciparum sickle-associated alleles (Pfsa

Identifiers

PMID42850325

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.