Evidence map›Paper›PMID 42848710›Full record

ArticleBiological research for nursing2026

Exploring Cross-Sectional and Longitudinal Associations Among DNA Methylation, Prognostic Proteins, and Symptoms in Patients Prescribed Oral Anticancer Medications for Multiple Myeloma.

Abigail Lustyik, Yvette P Conley, Catherine M Bender, Susan M Sereika, Zhirui Deng, Dianxu Ren, Corrine Bozich, Sarah M Belcher

Abstract read
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Article in Biological research for nursing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Abigail LustyikSchool of Nursing, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0009-0002-7056-9430
Yvette P ConleySchool of Nursing, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0002-1784-6067
Catherine M BenderSchool of Nursing, University of Pittsburgh, Pittsburgh, PA, USA.
Susan M SereikaSchool of Nursing, University of Pittsburgh, Pittsburgh, PA, USA.
Zhirui DengSchool of Nursing, University of Pittsburgh, Pittsburgh, PA, USA.
Dianxu RenSchool of Nursing, University of Pittsburgh, Pittsburgh, PA, USA.
Corrine BozichSchool of Nursing, University of Pittsburgh, Pittsburgh, PA, USA.
Sarah M BelcherSchool of Nursing, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0002-4095-295X

Funding

Targeting Research and Academic Training of Nurses in GenomicsT32NR009759 · NINR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CONLEY, YVETTE P · 2006 to 2025
$4.5M
Understanding Oral Anticancer Medication Adherence among Patients with Multiple MyelomaK23NR019296 · NINR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BELCHER, SARAH M. · 2020 to 2022
$368k
NINR NIH HHS K23 NR019296NINR NIH HHS T32 NR009759
6 · The paper itself

Abstract

At-home administration of oral anticancer medications (OAM) limits interactions with healthcare providers, therefore limiting opportunities for symptom management, posing threats to medication adherence. Individuals diagnosed with multiple myeloma (MM) experience symptoms from both disease- and treatment-related factors. Proteins Beta-2 Microglobulin (B2M) and Lactate Dehydrogenase (LDH) are routinely used in disease monitoring, yet their associations with symptoms and regulation via DNA methylation (DNAm) in individuals with MM have not been investigated. This study explored relationships among LDH and B2M proteins; DNAm of genes

Indexed as

medication adherencemulti-omicsmultiple myelomasymptoms

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.