Evidence map›Paper›PMID 42848434›Full record

ArticleeLife2026

Circadian photoreceptor CRYPTOCHROME promotes wakefulness under short winter-like days via a GABAergic circuitry.

Lixia Chen, Danya Tian, Chang Su, Luoying Zhang

Abstract read
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lixia ChenKey Laboratory of Molecular Biophysics of Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.ORCID https://orcid.org/0000-0002-1634-1729
Danya TianKey Laboratory of Molecular Biophysics of Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Chang SuKey Laboratory of Molecular Biophysics of Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Luoying ZhangKey Laboratory of Molecular Biophysics of Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.ORCID https://orcid.org/0000-0001-5996-6975

Funding

Ministry of Science and Technology of the People's Republic of China 2021ZD0203202Ministry of Science and Technology of the People's Republic of China 2024YFA1803201National Natural Science Foundation of China 32300984National Natural Science Foundation of China 32341021National Natural Science Foundation of China 82530044Science and Technology Department of Hubei Province 2022CFA049
6 · The paper itself

Abstract

A cardinal symptom of seasonal affective disorder (SAD, also known as winter depression) is hypersomnolence, while the cause of this 'winter sleepiness' is not known. Here, we found that lack of the circadian photoreceptor

Indexed as

Circadian RhythmCryptochromesDrosophila melanogasterDrosophila ProteinsGABAergic Neuronsgamma-Aminobutyric AcidWakefulnessAnimalsEye ProteinsPhotoperiodSeasonsSleepcry protein, DrosophilaCryptochromesDrosophila ProteinsEye Proteinsgamma-Aminobutyric Acidcircadian pacemakerCRYPTOCHROMED. melanogasterGABAneurosciencephotoperiodphotoreceptorwakefulness

Identifiers

PMID42848434
PMCPMC13649261

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.