ReviewTopics in current chemistry (Cham)2026
Synthetic Pathways to 1, 2-Dicarbonyl Compounds: Progress, Challenges, and Opportunities.
Review in Topics in current chemistry (Cham), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Authors and funding
3 authors.
Funding
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Abstract
1,2-Dicarbonyl compounds or α-dicarbonyls are important synthetic intermediates widely used in organic synthesis, medicinal chemistry, and materials science due to their unique reactivity and versatility. In recent years, significant progress has been made in developing efficient methods for synthesizing them from diverse substrates, including heterocycles, alkenes, alkynes, ketones, and aromatic systems. This review provides an overview of recent advances reported between 2014 and 2026, covering transition-metal-catalyzed, metal-free, photocatalytic, electrochemical, and catalyst-free strategies. Emphasis is placed on reaction mechanisms, substrate scope, functional-group tolerance, and sustainability. The limitations associated with substrate compatibility, cost-effectiveness, and sustainability are also critically discussed. Finally, emerging directions, such as green oxidants, heterogeneous catalysis, photocatalysis, and electrochemical methods, are highlighted as promising avenues for future development. This review aims to provide a comprehensive resource to guide the design of efficient and sustainable strategies for synthesizing 1,2-dicarbonyl compounds.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.