Evidence map›Paper›PMID 42848180›Full record

ArticleInfection2026

A three-generation mpox cluster in Chongqing, 2024: transmission chain investigation and phylogenetic characterization.

Tingting Li, Mingyue Wang, Chunyan Deng, Hua Zhao, Ya Wang, Yu Xia, Li Qi, Jiang Long

Abstract read
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In one paragraph

Article in Infection, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tingting Li *Chongqing Center for Disease Control and Prevention (Chongqing Academy of Preventive Medicine), No. 187, Tongxing North Road, Liangjiang New Area, Chongqing, 400707, China.
Mingyue Wang *Chongqing Center for Disease Control and Prevention (Chongqing Academy of Preventive Medicine), No. 187, Tongxing North Road, Liangjiang New Area, Chongqing, 400707, China.
Chunyan DengJiulongpo District Center for Disease Control and Prevention, Chongqing, 400039, China.
Hua ZhaoChongqing Center for Disease Control and Prevention (Chongqing Academy of Preventive Medicine), No. 187, Tongxing North Road, Liangjiang New Area, Chongqing, 400707, China.
Ya WangJiangjin District Center for Disease Control and Prevention, Chongqing, 402260, China.
Yu XiaChongqing Center for Disease Control and Prevention (Chongqing Academy of Preventive Medicine), No. 187, Tongxing North Road, Liangjiang New Area, Chongqing, 400707, China. 21524856@qq.com.
Li QiChongqing Center for Disease Control and Prevention (Chongqing Academy of Preventive Medicine), No. 187, Tongxing North Road, Liangjiang New Area, Chongqing, 400707, China. qili19812012@126.com.
Jiang LongChongqing Center for Disease Control and Prevention (Chongqing Academy of Preventive Medicine), No. 187, Tongxing North Road, Liangjiang New Area, Chongqing, 400707, China. 68803648@163.com.

Funding

Chinese Preventive Medicine Association CPMA2024CRBFKChongqing Municipal Science and Technology Bureau cstc2024ycjh-bgzxm0224National Key Research and Development Program of China 2024YFC2311500National Natural Science Foundation of China 12371503
6 · The paper itself

Abstract

backgroundIn recent years, mpox has emerged as a significant public health concern, with the potential for both local and international spread. This study aimed to describe a three-generation mpox cluster and characterize its epidemiological features.

methodsA three-generation mpox cluster was reported between August 19 and 23, 2024, in Chongqing China. Field epidemiology investigations were conducted to identify high-risk exposures and transmission routes and to guide the public health response. Rash lesion samples, anal swabs, pharyngeal swabs, and blood samples were collected from the cases for real-time polymerase chain reaction testing. Genome sequencing was performed to determine the MPXV clade.

resultsThe cluster comprised three men who have sex with men, aged in their 40s, 30s, and 20s, respectively. All cases had mild symptoms, including perianal or genital rashes. .Case B was exposed to Case A through condomless sexual intercourse four days before symptom onset in Case A. Epidemiological investigation supported transmission through condomless sexual contact along the Case A → B → C chain in August 2024. Samples from Cases A and C were successfully sequenced and identified as MPXV clade IIb, lineage E.3.

conclusionsThis three-generation mpox cluster was caused by MPXV clade IIb and was transmitted through condomless sexual contact. The findings suggest possible pre-symptomatic transmission of MPXV. Health education and sustained surveillance are essential for mpox prevention and control.

Indexed as

Infection controlMpoxPublic healthSexually transmitted diseasetransmission chain

Identifiers

PMID42848180

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.