Evidence map›Paper›PMID 42848066›Full record

ArticleNeuroradiology2026

Resting-state BOLD fMRI-derived cerebrovascular reactivity for detecting crossed cerebellar diaschisis.

Jie Xu, Yi Shan, Bixiao Cui, Yayan Yin, Jiayouzheng Li, Jing Liu, Yan Ma, Jie Lu

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Article in Neuroradiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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8 authors.

Jie Xu *Department of Radiology and Nuclear Medicine, Xuan Wu Hospital of the Capital Medical University, Beijing, China.
Yi Shan *Department of Radiology and Nuclear Medicine, Xuan Wu Hospital of the Capital Medical University, Beijing, China.
Bixiao CuiDepartment of Radiology and Nuclear Medicine, Xuan Wu Hospital of the Capital Medical University, Beijing, China.ORCID http://orcid.org/0000-0003-4353-4590
Yayan YinDepartment of Radiology and Nuclear Medicine, Xuan Wu Hospital of the Capital Medical University, Beijing, China.
Jiayouzheng LiDepartment of Radiology and Nuclear Medicine, Xuan Wu Hospital of the Capital Medical University, Beijing, China.
Jing LiuDepartment of Radiology and Nuclear Medicine, Xuan Wu Hospital of the Capital Medical University, Beijing, China.
Yan MaDepartment of Neurosurgery, Xuan Wu Hospital of the Capital Medical University, Beijing, China.
Jie LuDepartment of Radiology and Nuclear Medicine, Xuan Wu Hospital of the Capital Medical University, Beijing, China. imaginglu@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo study cerebellar cerebrovascular reactivity (CVR) derived from resting-state (RS) blood oxygen level-dependent (BOLD) as a potential imaging biomarker for crossed cerebellar diaschisis (CCD).

methodsThirty-nine patients with symptomatic unilateral cerebrovascular occlusion and eighteen age-matched healthy subjects underwent a simultaneous PET/MR scan. CCD was diagnosed as a contralateral cerebellar metabolic reduction present on

resultsIn our cohort, CCD was diagnosed in 21 of 39 (53.8%) patients on

conclusionRS BOLD-CVR demonstrates good sensitivity and specificity to detect diaschisis-related cerebellar cerebrovascular reactivity in patients with symptomatic unilateral cerebrovascular occlusion. Furthermore, participants with cerebellar CVR impairment and metabolic reduction tended to have poorer neurological function.

Indexed as

18F-FDG PETCerebrovascular occlusionCerebrovascular reactivityCrossed cerebellar diaschisisResting-state BOLDStroke

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.