ArticleNeuroradiology2026
Resting-state BOLD fMRI-derived cerebrovascular reactivity for detecting crossed cerebellar diaschisis.
Article in Neuroradiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo study cerebellar cerebrovascular reactivity (CVR) derived from resting-state (RS) blood oxygen level-dependent (BOLD) as a potential imaging biomarker for crossed cerebellar diaschisis (CCD).
methodsThirty-nine patients with symptomatic unilateral cerebrovascular occlusion and eighteen age-matched healthy subjects underwent a simultaneous PET/MR scan. CCD was diagnosed as a contralateral cerebellar metabolic reduction present on
resultsIn our cohort, CCD was diagnosed in 21 of 39 (53.8%) patients on
conclusionRS BOLD-CVR demonstrates good sensitivity and specificity to detect diaschisis-related cerebellar cerebrovascular reactivity in patients with symptomatic unilateral cerebrovascular occlusion. Furthermore, participants with cerebellar CVR impairment and metabolic reduction tended to have poorer neurological function.
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