Evidence map›Paper›PMID 42847337›Full record

ReviewEuropean journal of immunology2026

Cross-Neutralizing and Broadly Neutralizing Human Antibodies Against Nonenveloped Viruses.

Sarah Marchand, Samy Taouli, Dorian McIlroy

Abstract readReview
PubMed Publisher
In one paragraph

Review in European journal of immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sarah MarchandCenter for Research in Transplantation and Translational Immunology, Nantes Université, CHU Nantes, INSERM, UMR 1064, ITUN2, Nantes, France.
Samy TaouliCenter for Research in Transplantation and Translational Immunology, Nantes Université, CHU Nantes, INSERM, UMR 1064, ITUN2, Nantes, France.
Dorian McIlroyCenter for Research in Transplantation and Translational Immunology, Nantes Université, CHU Nantes, INSERM, UMR 1064, ITUN2, Nantes, France.

Funding

French Agence Nationale de la Recherche ANR-22-CE15-0043Pays de la Loire
6 · The paper itself

Abstract

Neutralizing antibodies (NAbs) play a central role in antiviral protection and are increasingly considered for prophylactic or therapeutic use, particularly against viruses lacking effective antiviral treatments. While research has predominantly focused on NAbs targeting the envelope proteins of enveloped viruses, nonenveloped viruses remain major human pathogens for which broad antibody responses are less well characterized. Recent work has identified several cross- and broadly neutralizing antibodies generated during human infection with nonenveloped viruses, revealing different mechanisms of action and new structural vulnerabilities. This review provides an overview of these NAbs, summarizes their mechanisms of action when these have been identified, and highlights recent advances relevant to antiviral antibody development and vaccine research.

Indexed as

Antibodies, NeutralizingAntibodies, ViralVirus DiseasesVirusesAnimalsCross ReactionsHumansAntibodies, NeutralizingAntibodies, Viral

Identifiers

PMID42847337

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.