Evidence map›Paper›PMID 42847105›Full record

ArticleGeriatrics, gerontology and aging2026

Barriers and facilitators to deprescribing in primary care in Brazil: a qualitative study of pharmacists' perspectives mapped to the Theoretical Domains Framework.

Milena Flores de Melo, Priscila Ribeiro Castro, Rafael Mota Pinheiro, Michael Alan Steinman, Patrick Alexander Wachholz, Marcio Galvão Oliveira

Abstract read
In one paragraph

Article in Geriatrics, gerontology and aging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Milena Flores de MeloInstituto Multidisciplinar em Saúde, Universidade Federal da Bahia - Vitória da Conquista (BA), Brazil.ORCID 0009-0001-2208-1169
Priscila Ribeiro CastroInstituto Multidisciplinar em Saúde, Universidade Federal da Bahia - Vitória da Conquista (BA), Brazil.ORCID 0000-0002-8455-6158
Rafael Mota PinheiroDepartamento de Farmácia, Universidade de Brasília - Brasília (DF), Brazil.ORCID 0000-0003-0348-6176
Michael Alan SteinmanDivision of Geriatrics, Department of Medicine, University of California San Francisco - San Francisco (CA), USA.ORCID 0000-0002-9564-9480
Patrick Alexander WachholzPrograma de Pós-Graduação em Pesquisa Clínica, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista - Botucatu (SP), Brazil.ORCID 0000-0002-4474-009X
Marcio Galvão OliveiraInstituto Multidisciplinar em Saúde, Universidade Federal da Bahia - Vitória da Conquista (BA), Brazil.ORCID 0000-0001-5281-7889

Funding

VARC CoreP30AG044281 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Alexander Keliimoeanu Smith · 2013 to 2026
$19.9M
The U.S. Deprescribing Research NetworkR33AG086944 · NIA · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI CYNTHIA Melinda BOYD, MICHAEL A. STEINMAN · 2024 to 2026
$2.5M
NIA NIH HHS P30 AG044281NIA NIH HHS R33 AG086944
6 · The paper itself

Abstract

Objective: To identify the main Barriers and facilitators to deprescribing from the perspective of primary care pharmacists in Brazil. Methods: In this qualitative secondary analysis, we analyzed brief written responses collected during a training session on medication deprescribing. Data were elicited through a SWOT (Strengths, Weaknesses, Opportunities, and Threats)-based structured activity and analyzed using qualitative content analysis. Emerging categories were subsequently interpreted through the Theoretical Domains Framework. Results: Responses were categorized into barriers (related to healthcare professionals, service structure, patients, and the healthcare model) and facilitators (advances in evidence, benefits of deprescribing, availability of resources, management support, and favorable attitudes among professionals and patients). These categories were mapped to Theoretical Domains Framework domains, including Beliefs about Consequences, Environmental Context and Resources, Social Influences, and Social/Professional Role and Identity. Conclusion: Implementing deprescribing in Brazil faces challenges but prospects are also promising. Adopting interprofessional approaches, educating patients, involving management, and investing in resources to strengthen primary health care are essential to optimize clinical outcomes and reduce health-related costs.

Indexed as

deprescribingpharmacistspolypharmacyprimary health carequalitative research

Identifiers

PMID42847105
PMCPMC13645382

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.