Bilateral Deep Vein Thrombosis in an Adolescent with Congenital Rubella Syndrome: A Case Report.

Highlights: Bilateral deep vein thrombosis is rare in adolescents and represents an uncommon presentation of venous thromboembolism.This case describes bilateral deep vein thrombosis in a patient with congenital rubella syndrome and chronic cardiovascular complications.Persistent bilateral lower limb edema in such patients should prompt consideration of deep vein thrombosis. Bilateral deep vein thrombosis (DVT) is a rare condition among adolescents and represents an uncommon pattern of venous thromboembolism. We report a case of bilateral DVT occurring in the setting of severe pulmonary hypertension and right-sided heart failure secondary to congenital heart disease associated with congenital rubella syndrome (CRS). A 19-year-old female patient, with a history of CRS characterized by the classical triad of unilateral cataract, sensorineural deafness, and congenital heart disease, was admitted to our hospital with shortness of breath, swelling in both legs, and abdominal discomfort. Doppler ultrasonography demonstrated partial thrombotic obstruction of the femoral, popliteal, and posterior tibial veins in both lower extremities. A diagnosis of DVT was established on the fourth day of hospitalization. This case highlights the importance of considering bilateral DVT in patients with CRS who present with lower extremity edema, particularly in the presence of cardiovascular complications.