Evidence map›Paper›PMID 42847000›Full record

ArticleFundamental research2026

Effects of early-life tactile experience enrichment on autistic-like behaviors and synaptic alterations in

Mingyue Liu, Guaiguai Ma, Yangming Zhang, Kezi Li, Fei Li, Tao Peng, Congcong Qin, Violeta G López-Huerta, Mario A Arias-Garcia, Wenting Wang and 3 more

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In one paragraph

Article in Fundamental research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mingyue LiuDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an 710032, China.
Guaiguai MaDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an 710032, China.
Yangming ZhangDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an 710032, China.
Kezi LiDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an 710032, China.
Fei LiDepartment of Neurosurgery, The Second Affiliated Hospital of Xi'an Medical University, Xi'an 710032, China.
Tao PengDepartment of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi'an 710032, China.
Congcong QinDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an 710032, China.
Violeta G López-HuertaInstitute of Cellular Physiology, National University of Mexico (UNAM), Mexico City 04510, Mexico.
Mario A Arias-GarciaFaculty of Psychology, National Autonomous University of Mexico, Mexico City 04510, Mexico.
Wenting WangDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an 710032, China.
Dayun FengDepartment of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi'an 710032, China.
Shengxi WuDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an 710032, China.
Baolin GuoDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an 710032, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autism spectrum disorder (ASD) presents a significant therapeutic challenge due to limited treatment options. While non-pharmacological approaches based on sensory stimulation have shown promise in clinical practice, the underlying mechanisms remain poorly understood. This study explored the therapeutic potential of tactile experience enrichment (TEE) during specific developmental windows in

Indexed as

Autism spectrum disorderRepetitive behaviorsSocial behaviorsSpineSynapseTactile experience enrichment

Identifiers

PMID42847000
PMCPMC13644509

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.