Evidence map›Paper›PMID 42846999›Full record

Trial reportFrontiers in nutrition2026

A randomized parallel-designed study evaluating the effect of an app-based nutritional concept for weight reduction and further cardiovascular risk factors: Insights from the PreVA study.

Lea Klein, Maren Biernath, Kristin Kipp, Michael Kiehntopf, Susann Scherag, Katharina Meier, Thomas Hübner, Stefan Lorkowski, Christine Dawczynski

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04717076 (PrevA Study - Evaluation of an App-based Nutritional Concept to Lower Cardiovascular Risk Factors), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04717076 nacompletednot on this map

PrevA Study - Evaluation of an App-based Nutritional Concept to Lower Cardiovascular Risk Factors (Focus: Weight Reduction)

TypeinterventionalSponsorUniversity of JenaRan2021 to 2021Enrolled80ConditionsReduction of Cardiovascular Risk FactorsArmsApp-based nutritional concept and fitness tracking, Nutritional concept with individual nutritional counselling, Nutritional concept without individual nutritional counselling
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lea KleinJunior Research Group Nutritional Concepts, Institute of Nutritional Sciences, Friedrich Schiller University Jena, Jena, Germany.
Maren BiernathJunior Research Group Nutritional Concepts, Institute of Nutritional Sciences, Friedrich Schiller University Jena, Jena, Germany.
Kristin KippDepartment of Pediatrics Weimar, Sophien- und Hufeland-Klinikum, Weimar, Germany.
Michael KiehntopfInstitute of Clinical Chemistry and Laboratory Diagnostics, University Hospital, Jena, Germany.
Susann ScheragPreventicus GmbH, Jena, Germany.
Katharina MeierPreventicus GmbH, Jena, Germany.
Thomas HübnerPreventicus GmbH, Jena, Germany.
Stefan LorkowskiCompetence Cluster for Nutrition and Cardiovascular Health (nutriCARD) Halle-Jena-Leipzig, Jena, Germany.
Christine DawczynskiJunior Research Group Nutritional Concepts, Institute of Nutritional Sciences, Friedrich Schiller University Jena, Jena, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Overweight is a major public health concern. Beyond traditional dietary therapy, mobile health (mHealth) applications have gained interest for their potential to support weight loss. However, evidence on their efficacy remains limited. This study evaluated the effectiveness of an app-based dietary concept for weight reduction and improvement of further cardiovascular risk factors. Methods: The PreVa study is a single-center, randomized, four-arm parallel intervention study comparing an app-based nutrition program with standard therapy involving personal counseling. Eighty adults with a body mass index between 25 and < 35 kg/m Results: After 12 weeks of energy reduction, weight loss was significantly greater in the intervention groups (-6.5 %, -7.3 %, -6.0 %) than in the control group (-2.1 %; Conclusion: The intervention groups achieved clinically meaningful weight loss and an improvement in blood lipid levels. The greatest effect is likely attributable to the individualized, nutrient-optimized menu plans rather than the type of counseling or delivery mode. Clinical trial registration: https://clinicaltrials.gov/, identifier NCT04717076.

Indexed as

Appcardiovascular risk factorsenergy intakenutritional conceptweight reduction

Identifiers

PMID42846999
PMCPMC13644689

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.