ArticleFood science & nutrition2026
Differential Associations of Dietary Inflammatory Index and Dietary Antioxidant Indices With Mortality Risk From MASLD/MetALD: Results From a Large Population-Based Study.
Article in Food science & nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Metabolic dysfunction-associated steatotic liver disease (MASLD) and its subtype, metabolic dysfunction and alcohol-associated liver disease (MetALD), represent escalating global health challenges. Despite the central role of dietary intervention in current guidelines, evidence remains limited regarding the synergistic impact of anti-inflammatory and antioxidant diets on the survival benefits of steatotic liver disease (SLD) populations, particularly those with moderate alcohol consumption. This study aims to elucidate the associations between dietary inflammatory/antioxidant quality and mortality across SLD subtypes, and provide insights into dietary recommendations for this patient group. Data from 3048 individuals (2146 MASLD, 902 MetALD) who participated in the 2005-2018 National Health and Nutrition Examination Survey were analyzed. Weighted Cox regression analysis was used to estimate the hazard ratios (HRs) and 95% confidence intervals (CIs) for mortality risk assessment. The mediation effects of inflammation-related indicators were explored by mediation analysis. During the follow-up period, a total of 306 deaths were documented. In MASLD patients, higher DII (T3) correlated with increased all-cause mortality (HR = 1.97, 95% CI: 1.12-3.47,
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