ArticleFrontiers in veterinary science2026
Comparative residue depletion and tissue distribution of three β-adrenergic agonists in broiler chickens.
Article in Frontiers in veterinary science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
β-Adrenergic agonists are banned as growth promoters in the European Union, and clenbuterol and salbutamol are routinely screened in poultry under national residue-control programs; characterizing their residue behavior in edible tissues therefore supports the detection of illicit use. This study examined the residue depletion and tissue distribution of salbutamol, clenbuterol, and terbutaline in 168 Ross 308 broiler chickens. Each compound was administered in drinking water at 2.5 or 5 mg/L for seven consecutive days, chosen to model a covert exposure route rather than an authorized feed protocol, followed by a withdrawal period. Concentrations in breast muscle, liver, and kidney were quantified using a validated LC-MS/MS method compliant with Commission Implementing Regulation (EU) 2021/808. Residue values are group mean concentrations of three birds per group per sampling point (
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