Evidence map›Paper›PMID 42846701›Full record

ArticleJournal of hazardous materials letters2026

Versatile TOP Assay Surrogates for Evaluating Oxidation Efficiency in Complex Environmental Samples.

Sarah Choyke, Hyun Yoon, Caroline Rose Alukkal, Youn Jeong Choi, Josie King, Collin Meyers, Jonathan Thorn, Hannah Kruelle, Anthony Grimaldi, Ben Priest and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of hazardous materials letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Sarah ChoykeEurofins Environment Testing, Arvada, CO, 80002, USA.
Hyun YoonDepartment of Civil and Environmental Engineering, University of California, Berkeley, CA 94720, USA.
Caroline Rose AlukkalDepartment of Environmental & Ecological Engineering, Purdue University, Lafayette, IN 47907, USA.
Youn Jeong ChoiDepartment of Environmental & Ecological Engineering, Purdue University, Lafayette, IN 47907, USA.
Josie KingDepartment of Civil & Environmental Engineering, University of Tennessee, Knoxville, TN 37996, USA.
Collin MeyersEurofins Environment Testing, Arvada, CO, 80002, USA.
Jonathan ThornEurofins Environment Testing, Lancaster, PA, 17601, USA.
Hannah KruelleEurofins Environment Testing, Lancaster, PA, 17601, USA.
Anthony GrimaldiEurofins Environment Testing, Arvada, CO, 80002, USA.
Ben PriestCambridge Isotope Laboratories, Tewksbury, MA 01876, USA.
Taryn McKnightEurofins Environment Testing, Arvada, CO, 80002, USA.
Ananya VisweswaranDepartment of Civil and Environmental Engineering, University of California, Berkeley, CA 94720, USA.
James GrayUnited States Geological Survey, Lakewood, CO 75240, USA.
Linda S LeeDepartment of Environmental & Ecological Engineering, Purdue University, Lafayette, IN 47907, USA.
Lisa Alvarez-CohenDepartment of Civil and Environmental Engineering, University of California, Berkeley, CA 94720, USA.
David L SedlakDepartment of Civil and Environmental Engineering, University of California, Berkeley, CA 94720, USA.
Mohamed AteiaAECOM, Dallas, TX 75240, USA.
Fuhar DixitDepartment of Civil and Environmental Engineering, University of California, Berkeley, CA 94720, USA.

Funding

Training CoreP42ES004705 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI SMITH, MARTYN T · 1987 to 2025
$74.6M
NIEHS NIH HHS P42 ES004705
6 · The paper itself

Abstract

Accurate assessment of total per- and polyfluoroalkyl substance (PFAS) contamination remains limited because conventional targeted analyses do not capture unknown precursor compounds. The total oxidizable precursor (TOP) assay has been widely used to address this gap; however, previous studies have shown that matrix effects can cause incomplete oxidation of precursors, which can be detected with a stable-isotope labeled oxidation surrogate. Yet, current surrogates are incompatible with EPA Method 1633A. Here, we introduce a new isotopically labeled surrogate system that integrates isotopically labeled surrogates -

Indexed as

AFFFEPA 1633Landfill leachatePFAS PrecursorsUV-TOP

Identifiers

PMID42846701
PMCPMC13645385

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.