Evidence map›Paper›PMID 42846630›Full record

ArticleRSC advances2026

Development of alendronate-loaded 3D-printed PCL/LDH scaffolds for controlled drug delivery in bone tissue engineering.

Mohammad Amin Shirazian, Aryan Ekhlasi, Ghazal Belgheisi, Masoumeh Haghbin Nazarpak, Mehran Solati-Hashjin

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mohammad Amin ShirazianDepartment of Biomedical Engineering, Amirkabir University of Technology (Tehran Polytechnic) Iran.
Aryan EkhlasiDepartment of Biomedical Engineering, Amirkabir University of Technology (Tehran Polytechnic) Iran.ORCID https://orcid.org/0000-0002-6080-7610
Ghazal BelgheisiDepartment of Biomedical Engineering, Amirkabir University of Technology (Tehran Polytechnic) Iran.
Masoumeh Haghbin NazarpakDepartment of Polymer and Color Engineering, Amirkabir University of Technology (Tehran Polytechnic) Iran haghbin@aut.ac.ir.ORCID https://orcid.org/0000-0002-3248-974X
Mehran Solati-HashjinDepartment of Biomedical Engineering, Amirkabir University of Technology (Tehran Polytechnic) Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone tissue engineering has made significant advances in recent years; however, the development of scaffolds that not only support tissue regeneration but also effectively deliver therapeutic agents remains a major challenge. The present study investigates the fabrication and evaluation of 3D-printed polycaprolactone (PCL)/layered double hydroxide (LDH) hybrid scaffolds incorporating alendronate (ALN) for bone tissue engineering applications. First, LDH particles were synthesized

Identifiers

PMID42846630
PMCPMC13644931

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.