Evidence map›Paper›PMID 42846489›Full record

SynthesisFrontiers in radiology2026

Incidence, risk factors, and outcomes of contrast-associated acute kidney injury following interventional radiology procedures: a systematic review and meta-analysis.

Saad Alhumaid, Mohammed Yousef Almulhim, Hessah Abdulaziz Al Hussaini, Qasem M Alalwan, Hani Almohammed Ali, Sarah A Al Ruzaihan, Fatima A Aborshaid, Abdulrhman Khaled Al Abdulqader, Nourah Al Dossary, Muneera Alabdulqader and 2 more

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Saad AlhumaidMinistry of Health, Pharmacy Department, King Fahad Hofuf Hospital, Al-Ahsa Health Cluster, Al-Ahsa, Saudi Arabia.
Mohammed Yousef AlmulhimDivision of Nephrology, Department of Internal Medicine, King Faisal University, Al-Ahsa, Saudi Arabia.
Hessah Abdulaziz Al HussainiDivision of Endocrinology, Department of Internal Medicine, King Faisal University, Al-Ahsa, Saudi Arabia.
Qasem M AlalwanRadiology Department, King Fahad Hofuf Hospital, Al-Ahsa Health Cluster, Ministry of Health, Al-Ahsa, Saudi Arabia.
Hani Almohammed AliRadiology Department, King Fahad Hofuf Hospital, Al-Ahsa Health Cluster, Ministry of Health, Al-Ahsa, Saudi Arabia.
Sarah A Al RuzaihanDepartment of Internal Medicine, College of Medicine, King Faisal University, Al-Ahsa, Saudi Arabia.
Fatima A AborshaidDepartment of Pediatric Allergy, Asthma and Clinical Immunology, Dr. Sulaiman Al-Habib Hospital, Al Khobar, Saudi Arabia.
Abdulrhman Khaled Al AbdulqaderDepartment of Internal Medicine, College of Medicine, King Faisal University, Al-Ahsa, Saudi Arabia.
Nourah Al DossaryMinistry of Health, General Surgery Department, King Fahad Hofuf Hospital, Al-Ahsa Health Cluster, Al-Ahsa, Saudi Arabia.
Muneera AlabdulqaderPediatric Nephrology Specialty, Pediatric Department, Medical College, King Faisal University, Al-Ahsa, Saudi Arabia.
Shaden Saleh AlMousaDivision of Radiology, Department of General Surgery, College of Medicine, King Faisal University, Al-Ahsa, Saudi Arabia.
Khalid Suliman AljoqimanDivision of Radiology, Department of General Surgery, College of Medicine, King Faisal University, Al-Ahsa, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Contrast-associated acute kidney injury (CA-AKI) is a recognized complication of iodinated contrast administration. Although extensively studied in coronary angiography, its incidence, associated factors, and outcomes following interventional radiology and other non-coronary endovascular procedures remain incompletely characterized. We evaluated the incidence, associated factors, and outcomes of CA-AKI in these populations. Methods: This systematic review followed PRISMA 2020 guidelines and a prospectively registered PROSPERO protocol (CRD420261385592). PubMed/MEDLINE, Embase, Scopus, CINAHL, and Web of Science were searched from inception to 30 April 2026. Eligible studies evaluated CA-AKI following catheter-based non-coronary endovascular or interventional radiology procedures. Random-effects meta-analysis estimated pooled incidence, with subgroup and sensitivity analyses. Results: Thirty-nine studies were included, of which 38 contributed to the meta-analysis. The pooled CA-AKI incidence was 6.91% (95% CI 5.69-8.24; I Conclusion: CA-AKI occurs after a range of non-coronary endovascular and interventional radiology procedures and may be associated with clinically important adverse outcomes. Substantial heterogeneity limits the generalizability of a single pooled incidence estimate, and procedure- and population-specific estimates should remain central to interpretation. Standardised definitions and prospective multicentre studies are needed to establish procedure-specific risk profiles and clinically useful preventive strategies. Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD420261385592, PROSPERO, CRD420261385592.

Indexed as

clinical outcomescontrast-associated acute kidney injurycontrast-induced nephropathyincidenceinterventional radiologyiodinated contrast mediarisk factors

Identifiers

PMID42846489
PMCPMC13642721

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.