Evidence map›Paper›PMID 42846462›Full record

ArticleGastroenterology report2026

Prediction of endoscopic postoperative recurrence in Crohn's disease: a nationwide multicenter real-world cohort from China.

Fan Hu, Zicheng Huang, Liangru Zhu, Qian Cao, Hong Guo, Yu Fu, Lingjie Huang, Lingya Xiang, Kang Chao, Chao Wang and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gastroenterology report, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Fan HuDepartment of Gastroenterology, The First Affiliated Hospital, Sun Yat-sen University, No. 58 Zhongshan Er Road, Yuexiu District, Guangzhou, Guangdong 510062, P. R. China.ORCID https://orcid.org/0000-0002-6638-8744
Zicheng HuangDepartment of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-sen University, No. 26 Yuancun Erheng Road, Tianhe District, Guangzhou, Guangdong 510655, P. R. China.
Liangru ZhuDepartment of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Jianghan District, Wuhan, Hubei 430022, P. R. China.ORCID https://orcid.org/0000-0002-7372-294X
Qian CaoDepartment of Gastroenterology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, No. 3 East Qingchun Road, Shangcheng District, Hangzhou, Zhejiang 310016, P. R. China.
Hong GuoDepartment of Gastroenterology, Chongqing General Hospital, Chongqing University, No. 118 Xingguang Avenue, Liangjiang New Area, Chongqing 401147, P. R. China.ORCID https://orcid.org/0000-0002-7056-0586
Yu FuDepartment of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Jianghan District, Wuhan, Hubei 430022, P. R. China.ORCID https://orcid.org/0000-0001-8878-3131
Lingjie HuangDepartment of Gastroenterology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, No. 3 East Qingchun Road, Shangcheng District, Hangzhou, Zhejiang 310016, P. R. China.
Lingya XiangInflammatory Bowel Disease Center, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, No. 3 East Qingchun Road, Shangcheng District, Hangzhou, Zhejiang 310016, P. R. China.
Kang ChaoDepartment of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-sen University, No. 26 Yuancun Erheng Road, Tianhe District, Guangzhou, Guangdong 510655, P. R. China.
Chao WangDepartment of Pathology, The Sixth Affiliated Hospital, Sun Yat-sen University, No. 26 Yuancun Erheng Road, Tianhe District, Guangzhou, Guangdong 510655, P. R. China.
Xiang GaoDepartment of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-sen University, No. 26 Yuancun Erheng Road, Tianhe District, Guangzhou, Guangdong 510655, P. R. China.ORCID https://orcid.org/0000-0002-3058-4655
Minhu ChenDepartment of Gastroenterology, The First Affiliated Hospital, Sun Yat-sen University, No. 58 Zhongshan Er Road, Yuexiu District, Guangzhou, Guangdong 510062, P. R. China.ORCID https://orcid.org/0000-0001-8181-0846

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Preventing endoscopic postoperative recurrence (ePOR) remains a major challenge in Crohn's disease (CD). This study aimed to identify the clinical and histopathological predictors of CD ePOR. Methods: This nationwide, multicenter retrospective cohort study included 389 CD patients from five tertiary Chinese IBD centers, all of whom underwent curative ileocolonic resection between July 2016 and June 2024. The primary endpoint was ePOR at 6-12 months after surgery, defined as a modified Rutgeerts' score of ≥ i2b. Prediction models were developed based on the result of multivariate analysis of clinical and pathological data. Results: The overall ePOR rate was 24.9%. Multivariate analysis showed that prior exposure to biologics [odds ratio (OR) 2.695, 95% confidence interval (CI) 1.605-4.525, Conclusions: In the era of biologics and perioperative optimization, the 6-12-month ePOR rate among CD patients was 24.9%. A combined clinical-pathological model showed strong predictive performance.

Indexed as

Crohn’s diseaseendoscopic recurrencepathologicpostoperativeprediction model

Identifiers

PMID42846462
PMCPMC13644528

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.