Evidence map›Paper›PMID 42846339›Full record

ArticleFrontiers in microbiology2026

High-affinity chicken scFv antibodies recognize recombinant VP1-CDEF' protein and native virions of feline calicivirus genotype II strain LZ2023.

Yanquan Wei, Yihan Liu, Zhen Han, Huitian Gou, Kaiqi Lian, Dongdong Sun, Yanhong Ji, Hongmei Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yanquan WeiCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, China.
Yihan LiuCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, China.
Zhen HanSichuan Purity Pharmaceutical Co., Ltd., Chengdu, China.
Huitian GouCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, China.
Kaiqi LianSchool of Biological and Food Engineering, Anyang Institute of Technology, Anyang, China.
Dongdong SunState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, China.
Yanhong JiState Key Laboratory for Animal Disease Control and Prevention, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.
Hongmei WangCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Feline calicivirus (FCV) is a significant pathogen responsible for upper respiratory tract disease and oral ulceration in felids. Genetic and antigenic variation in circulating FCV strains limits the utility of current diagnostic assays, and no validated genotype II-specific antibodies exist for rapid test development. In this study, we targeted the C, D, E, and partial F regions of the major capsid protein VP1 (termed VP1-CDEF'). The recombinant VP1-CDEF' protein was expressed in a prokaryotic system and used to immunize SPF chickens. A chicken-derived phage display single-chain variable fragment (scFv) library was successfully constructed, with a capacity of 5.25 × 10

Indexed as

biolayer interferometryengineered antibodyfeline calicivirusphage displaysingle-chain variable fragment

Identifiers

PMID42846339
PMCPMC13642595

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.