ArticleFrontiers in psychiatry2026
Neural mechanisms of guided internet-based cognitive behavioral therapy for children with attention-deficit/hyperactivity disorder: a protocol for a prospective multimodal MRI study.
Article in Frontiers in psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Attention-deficit/hyperactivity disorder (ADHD), a common neurodevelopmental disorder in childhood, is associated with academic, social, and emotional difficulties. Although pharmacotherapy is widely used for treating ADHD, functional impairments often remain. Cognitive behavioral therapy (CBT) has demonstrated benefits in children with ADHD, and internet-based CBT (ICBT) may improve treatment accessibility. However, the neurobiological mechanisms underlying ICBT remain unclear, and neural markers predicting treatment responses have not been well established, particularly in children with ADHD. Neuroimaging may aid in the exploration of changes in the brain structure and function that are associated with interventions and provide insights into predictors of treatment response. Methods and analysis: This multimodal neuroimaging study aims to examine intervention-related neural changes in children with ADHD using pre- and post-intervention MRI assessments. Participants will be drawn from a cohort of participants of an ongoing randomized, sham-controlled ICBT clinical trial and will thus belong to an ICBT or sham control group. Approximately 60 children with ADHD will undergo multimodal magnetic resonance imaging (MRI), including structural MRI, resting-state functional MRI, and diffusion tensor imaging before and after an 11-week intervention. MRI data from typically developing (TD) children will be obtained from an ongoing neuroimaging database for baseline cross-sectional comparisons and as a reference for interpreting post-intervention neural changes in the ADHD group. Analyses will explore intervention-related changes in brain structure and function, as well as associations between baseline MRI markers and clinical treatment response. Ethics and dissemination: This study was approved by the Research Ethics Committee of the University of Fukui Hospital in February 2026 (ethics approval number: 20250238). Participant recruitment commenced in March 2026. The study findings will be disseminated through peer-reviewed journals and scientific conferences.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.