Evidence map›Paper›PMID 42846206›Full record

ArticleEFSA journal. European Food Safety Authority2026

Assessment of guanidinoacetic acid (GAA) and a preparation of GAA (Creamino®) as feed additives for chickens for fattening and reared for breeding/laying, weaned piglets and pigs for fattening, for the renewal of their authorisation and its extension of use to suckling piglets (Alzchem Trostberg GmbH).

EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba and 13 more

Abstract read
In one paragraph

Article in EFSA journal. European Food Safety Authority, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
Roberto Edoardo Villa
Giovanna Azimonti
Eleftherios Bonos
Henrik Christensen
Mojca Durjava
Birgit Dusemund
Ronette Gehring
Boet Glandorf
Maryline Kouba
Marta López-Alonso
Francesca Marcon
Giovanna Martelli
Carlo Nebbia
Alena Pechová
Miguel Prieto-Maradona
Katerina Theodoridou
Nuria Duran
Jaume Galobart
Jordi Ortuño
Maria Vittoria Vettori
Alberto Navarro-Villa
Elena Abenza

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the feed additives guanidinoacetic acid (GAA) and a preparation of GAA (Creamino®) for chickens for fattening and reared for laying and breeding, weaned piglets and pigs for fattening for the renewal of their authorisation and their extension of use in feed for suckling pigs. The additives are already authorised for use in chickens for fattening and reared for laying and breeding, weaned piglets and pigs for fattening. The FEEDAP Panel concludes that the additives remain safe for the target species, consumers and environment and that the extension of the use to suckling piglets would not affect these conclusions. Regarding user safety, the additives were not considered irritant to skin or eyes and were not considered a potential skin sensitiser. There is no need for assessing the efficacy of the additives in the context of the renewal of the authorisation for chickens for fattening, chickens reared for laying and breeding, weaned piglets and pigs for fattening. The Panel concludes that the additives are efficacious in feed for suckling piglets at 600 mg/kg complete feed.

Indexed as

creaminoefficacyguanidinoacetic acidimprovement of performance parameterssafetyzootechnical additives

Identifiers

PMID42846206
PMCPMC13643648

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.