ArticleJournal of parasitology research2026
Frequency of Mutations Within P-Glycoprotein and Beta-Tubulin Associated With Ivermectin Treatment in
Rufus Akinkagle, Millicent Opoku, Millicent Selassie Afatodzie, Joseph Harold Nyarko Osei, Sampson Otoo, Sarah-Sally Mawunyo Dogbe, Abena Akyeamaa Nyarko, Martin N Donkor, Mawuli K Azameti, Iddrisu Fuseini and 4 more
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In one paragraphArticle in Journal of parasitology research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
14 authors.
Millicent OpokuDepartment of Parasite and Vector Biology Noguchi Memorial Institute for Medical Research College of Health Sciences University of Ghana Legon Ghana ug.edu.gh.ORCID https://orcid.org/0000-0003-0074-1661 Millicent Selassie AfatodzieDepartment of Parasite and Vector Biology Noguchi Memorial Institute for Medical Research College of Health Sciences University of Ghana Legon Ghana ug.edu.gh.
Sampson OtooDepartment of Parasite and Vector Biology Noguchi Memorial Institute for Medical Research College of Health Sciences University of Ghana Legon Ghana ug.edu.gh.
Sarah-Sally Mawunyo DogbeDepartment of Parasite and Vector Biology Noguchi Memorial Institute for Medical Research College of Health Sciences University of Ghana Legon Ghana ug.edu.gh.
Abena Akyeamaa NyarkoDepartment of Parasite and Vector Biology Noguchi Memorial Institute for Medical Research College of Health Sciences University of Ghana Legon Ghana ug.edu.gh.
Martin N DonkorDepartment of Biochemistry and Forensic Sciences School of Chemical and Biochemical Sciences University of Technology and Applied Sciences Navrongo Ghana hct.edu.om.ORCID https://orcid.org/0000-0002-0564-2956 Mawuli K AzametiDepartment of Applied Biology School of Environment and Life Sciences University of Technology and Applied Sciences Navrongo Ghana hct.edu.om.
Iddrisu FuseiniDepartment of Applied Biology School of Environment and Life Sciences University of Technology and Applied Sciences Navrongo Ghana hct.edu.om.
Sellase Pi-BansaDepartment of Parasite and Vector Biology Noguchi Memorial Institute for Medical Research College of Health Sciences University of Ghana Legon Ghana ug.edu.gh.
Daniel Adjei BoakyeDepartment of Parasite and Vector Biology Noguchi Memorial Institute for Medical Research College of Health Sciences University of Ghana Legon Ghana ug.edu.gh.
Kwadwo Kyereme FrempongDepartment of Parasite and Vector Biology Noguchi Memorial Institute for Medical Research College of Health Sciences University of Ghana Legon Ghana ug.edu.gh.ORCID https://orcid.org/0000-0002-1747-5286 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Background: Ivermectin is the drug of choice for the control of onchocerciasis because of its potent embryostatic and microfilaricidal effect. However, with long periods of mass drug administration, the effect of ivermectin on the Methods: Results: A total of 45 adult female worms were obtained from 33 participants, and about 40% of these worms were reproductively active. High frequencies of mutant genes observed in parasite population (91.1%) for the Conclusion: This study shows a high frequency of mutations in both
Indexed as
adult female wormbeta-tubulinfrequencies of mutationsGhanaivermectinOnchocerca volvulusonchocerciasisp-glycoprotein
Identifiers
PMID42846198
PMCPMC13643362
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