ArticleCureus2026
Clinical Evaluation of Polyglycolic Acid Sheet Application After Partial Glossectomy: A Retrospective Analysis of 284 Consecutive Cases.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
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Abstract
objectiveTo evaluate the clinical outcomes of polyglycolic acid (PGA) sheet application with fibrin glue after partial glossectomy, comparing Neoveil and Neoveil Nano sheets, and to identify factors affecting sheet detachment, postoperative bleeding, and granuloma-like neoplasm (GLN) development. STUDY
designWe retrospectively analyzed 284 consecutive patients who underwent partial glossectomy with PGA sheet coverage between February 2011 and November 2025. Two sheet types were used: Neoveil (n = 169) and Neoveil Nano (n = 115). The primary outcome was sheet detachment; secondary outcomes were postoperative bleeding and GLN development. Multivariable modified Poisson regression was performed.
resultsThe overall engraftment rate was 81.3% (231/284). Neoveil Nano showed significantly higher engraftment (98.3%) than Neoveil (69.8%). Multivariable analysis revealed that Neoveil Nano (risk ratio (RR) = 0.079, 95% confidence interval (CI): 0.019-0.325, P < 0.001) and electrical scalpel use (RR = 0.468, 95% CI: 0.268-0.819, P = 0.008) were independent protective factors against detachment. Postoperative bleeding occurred in 6.3% (18/284). GLN developed in 10.9% (31/284), with a median onset of 53.0 days. Patients with wound-healing-impaired conditions showed a numerically higher GLN rate (17.0% vs 9.7%) and earlier onset.
conclusionsNeoveil Nano PGA sheets demonstrate superior engraftment compared with conventional Neoveil after partial glossectomy. Electrical scalpel resection also improves engraftment. Sheet detachment was strongly associated with postoperative bleeding, highlighting the importance of sheet adhesion during early wound healing.
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