Evidence map›Paper›PMID 42846028›Full record

ArticleFrontiers in medicine2026

Multicenter study on ultrasound characteristics of acupoints in the Hand Yangming Meridian and related factors.

Fangqin Liu, Yunhao Luo, Jiaojun Yan, Zhengyan Wang, Shiping Wu, Shuting Li, Xuhong Nan, Chunxia Cheng, Xuerong Fu, Yalin Lu and 4 more

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Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Fangqin Liu *School of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Yunhao Luo *Department of Ultrasound, West China Hospital of Sichuan University, Chengdu, China.
Jiaojun YanDepartment of Ultrasound, Sichuan Integrative Medicine Hospital, Chengdu, China.
Zhengyan WangRehabilitation Medicine Department, Sichuan Integrative Medicine Hospital, Chengdu, China.
Shiping WuDepartment of Ultrasound, Suining Traditional Chinese Medicine Hospital, Suining, Sichuan, China.
Shuting LiDepartment of Ultrasound, Chengdu Integrated TCM & Western Medicine Hospital, Chengdu, China.
Xuhong NanDepartment of Ultrasound, Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Chunxia ChengDepartment of Ultrasound, The Affiliated Traditional Chinese Medicine Hospital Southwest Medical, Chengdu, China.
Xuerong FuDepartment of Ultrasound, The Traditional Chinese Medicine Hospital of Longquanyi, Chengdu, China.
Yalin LuDepartment of Ultrasound, Sichuan Tianfu New Area People's Hospital, Chengdu, China.
Xuemei XiaDepartment of Ultrasound, Deyang Integrated Traditional Chinese and Western Medicine Hospital, Deyang, China.
Huan DuDepartment of Ultrasound, Mianyang Hospital of the Traditional Chinese Medicine, Mianyang, China.
Zhengchao FanDepartment of Ultrasound, Sichuan Second Hospital of The Traditional Chinese Medicine, Chengdu, China.
Lang QiaoDepartment of Ultrasound, Sichuan Integrative Medicine Hospital, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate sonographic characteristics and influencing factors of Hegu (LI 4), Xialian (LI 8) and Shousanli (LI 10) on the Hand-Yangming Large Intestine Meridian via multimodal ultrasonography. Methods: In total of 110 healthy volunteers were recruited across multiple centers, with standardized localization of Hegu(HG, LI 4), Xialian(XL, LI 8) andshousanli(SSL, LI 10) performed. Grayscale ultrasonography, color Doppler flow imaging and shear wave elastography were used for ultrasonic data acquisition. Needle tip depth, acupoint-bone adjacent distance, tissue composition, blood perfusion and biomechanical properties at acupoints were quantitatively detected. Results: Baseline information and observational indices were consistent among research centers ( Conclusions: Acupoints of the Hand-Yangming Large Intestine Meridian have specific ultrasonic manifestations, including definite anatomical location, tight fascial attachment, increasing fascial correlation along the meridian, and superior local tissue biomechanics. This study provides quantitative ultrasonic evidence for the meridian-connective tissue hypothesis, and offers a practical method for exploring acupuncture mechanisms.

Indexed as

acupointacupunctureelasticity imaging techniquesmechanismultrasonography

Identifiers

PMID42846028
PMCPMC13642146

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