ArticleFrontiers in cardiovascular medicine2026
Diagnostic value of left atrial three-dimensional strain for paroxysmal atrial fibrillation in patients with acute ischemic stroke.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To investigate the diagnostic and incremental value of left atrial three-dimensional (3D) strain parameters for paroxysmal atrial fibrillation (PAF) detected by short-term in-hospital cardiac monitoring and early Holter recording in patients with acute ischemic stroke (AIS). Methods: A total of 340 consecutive AIS patients were enrolled and divided into non-PAF ( Results: All 3D left atrial strain parameters showed diagnostic value for PAF [all area under the curve (AUC) > 0.6]. The base model incorporating age, sex, B-type natriuretic peptide (BNP, log-transformed), and left atrial maximum volume index (LAVI) yielded a C-index of 0.910. After adding left atrial reservoir-phase circumferential strain (LASr-c), the C-index increased to 0.932, with a continuous NRI of 0.8638 and IDI of 0.0973. Bootstrap validation confirmed model robustness (bias-corrected C-index = 0.919). DCA showed that the new model provided greater net clinical benefit across most risk threshold ranges. Conclusion: Left atrial 3D strain has good diagnostic value for in-hospital detected PAF in AIS patients. Adding LASr-c may improve PAF risk stratification and inform subsequent targeted rhythm monitoring.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.