ArticleFrontiers in medicine2026
A case report of primary bilateral macronodular adrenal hyperplasia caused by a novel
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Case presentation: A 59-year-old man was admitted because of long-standing poor glycemic and blood pressure control. Endocrine evaluation showed suppressed plasma adrenocorticotropic hormone (ACTH) levels, loss of the circadian cortisol rhythm, and failure of cortisol suppression after the low-dose dexamethasone suppression test. Imaging revealed multiple bilateral adrenal nodules. Histopathological examination showed nodular lesions composed predominantly of clear, lipid-rich cells, with a small number of cells with eosinophilic cytoplasm at the periphery of the nodules. Genetic testing identified an Conclusion: This case confirms PBMAH caused by a novel nonsense variant in
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