ArticleFrontiers in neurology2026
MINDSET 2.0: feasibility of digital decision support for epilepsy self-management.
Article in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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10 authors.
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Abstract
Background: The Managing Epilepsy Well Network (MEWN) epilepsy self-management (ESM) training programs assist people with epilepsy (PWE) in improving their ESM and co-morbidities. The online bilingual Management Information & Decision Support Epilepsy Tool (MINDSET) was enhanced to provide recommendations for these programs and to assess non-medical drivers of health (NMDH). Purpose: This study aimed to assess the feasibility of MINDSET 2.0, guided by Bowen et al.'s feasibility framework, and its perceived efficacy in providing PWE and healthcare providers with a tailored goal-based action plan, including ESM program recommendations and identified NMDH. Methods: A single-group feasibility trial was conducted from March to August 2022 with seven adult PWE in Arizona ( Results: Participants rated MINDSET 2.0 as acceptable, likable, credible, easy to use, appealing (100% agreement), of appropriate duration (83%), easy to understand (67%), impactful for managing epilepsy (75-100%), and found the program helpful (100%). The MINDSET 2.0 recommendation algorithms demonstrated 100% agreement between programmed and generated recommendations, confirming that the software executed the predefined decision rules as intended. Clinical feasibility of MINDSET 2.0 was evaluated separately through usability, acceptability, and implementation-related measures. Three participants needed help using MINDSET 2.0 (50%). Neurologists ( Conclusion: In addition to generating an ESM action plan, MINDSET 2.0 may be feasible in assisting PWE and neurologists in decision-making regarding the most suitable MEWN ESM training programs and the most pressing NMDH. Given that no participants reported prior experience with MEW programs, these ratings likely reflect participants' familiarity with and initial impressions of the recommended interventions rather than direct evaluations of their value or effectiveness. Further efficacy testing is required.
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