Evidence map›Paper›PMID 42845725›Full record

ArticleResearch square2026

The Effectiveness of Compensatory Cognitive Interventions in Mild Cognitive Impairment: A Meta-Analysis.

Anne Milner, Tanya Horwitz, Diya Tuli, Suqing Xie, Diya Sharma, Rachel Alison De La Merced, Allison Harvey

Abstract readPreprint
In one paragraph

Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anne MilnerUniversity of California, Berkeley.ORCID 0000-0002-5654-298X
Tanya HorwitzUniversity of California, Berkeley.
Diya TuliUniversity of California, Berkeley.
Suqing XieUniversity of California, Berkeley.
Diya SharmaUniversity of California, Berkeley.
Rachel Alison De La MercedUniversity of California, Berkeley.
Allison HarveyUniversity of California, Berkeley.

Funding

Improving sleep and circadian functioning, daytime functioning, and well-being for midlife and older adults by improving patient memory for a transdiagnostic sleep and circadian treatmentR01AG082651 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI Allison G Harvey · 2023 to 2026
$2.5M
NIA NIH HHS R01 AG082651
6 · The paper itself

Abstract

Background: Cognitive interventions that incorporate compensatory strategies may be particularly effective for individuals with Mild Cognitive Impairment (MCI). This meta-analysis evaluated the efficacy of compensatory cognitive interventions for individuals with MCI. Specifically, the following were evaluated: (1) the overall efficacy across cognitive outcomes, (2) effectiveness on different cognitive domains, and (3) influence of study-level moderators. Method: Database searches were conducted, and relevant studies were screened for inclusion criteria and underwent data extraction. A meta-analysis was performed across 23 included studies, followed by subgroup moderator and sensitivity analyses. Results: The overall pooled effect size across all cognitive outcomes was Conclusion: Compensatory-based interventions offer small-to-moderate benefits for individuals with MCI, particularly in the domains of memory and attention/working memory. While study-level moderators did not demonstrate significant differences, trends suggest that multicomponent approaches, using both external and internal strategies, and a group intervention format may confer some benefits.

Indexed as

cognitive interventionscompensatory strategiesmemoryMild Cognitive Impairment

Identifiers

PMID42845725
PMCPMC13640910

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.