ArticlebioRxiv : the preprint server for biology2026
Loss of
Zeinab Dehghani-Ghobadi, Eunah Chung, Azadeh Haghighitalab, Mohammed Sayed, Christopher Ahn, Yueh-Chiang Hu, Hee-Woong Lim, Joo-Seop Park
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
8 authors.
Zeinab Dehghani-GhobadiFeinberg Cardiovascular & Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Eunah ChungFeinberg Cardiovascular & Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Azadeh HaghighitalabFeinberg Cardiovascular & Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Mohammed SayedDivision of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Christopher AhnDivision of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Yueh-Chiang HuDivision of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Hee-Woong LimDivision of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Joo-Seop ParkFeinberg Cardiovascular & Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID 0000-0002-4190-4386 Funding
Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Daniela E Matei · 1993 to 2026
$153.9MThe Role of Renal Interstitium in Kidney DevelopmentR01DK127634 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI CARROLL, THOMAS JOSEPH, PARK, JOO-SEOP · 2021 to 2024
$2.8MHox Genes & Lineage InfidelityR01DK120842 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PARK, JOO-SEOP · 2019 to 2023
$2.5MHedgehog gene regulatory networks in the mammalian kidneyR01DK131052 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PARK, JOO-SEOP · 2022 to 2025
$1.9MRetinoic acid gene regulatory networks in the mammalian kidneyR01DK120847 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PARK, JOO-SEOP · 2019 to 2022
$1.7MGene regulatory networks in the proximal tubules of the mammalian kidneyR01DK125577 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PARK, JOO-SEOP · 2020 to 2022
$1.4MNCI NIH HHS P30 CA060553NIDDK NIH HHS R01 DK120842NIDDK NIH HHS R01 DK120847NIDDK NIH HHS R01 DK125577NIDDK NIH HHS R01 DK127634NIDDK NIH HHS R01 DK131052
6 · The paper itselfAbstract
HNF1B is a transcription factor required for proximal tubule (PT) specification during kidney development, but whether it is also required to maintain PT identity after differentiation remains unknown. Using PT-specific genetic deletion in mice, we found that loss of
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PMID42845647
PMCPMC13640791
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