Evidence map›Paper›PMID 42845589›Full record

ArticlebioRxiv : the preprint server for biology2026

Intrinsic protein disorder reveals divergent signaling architectures and lifestyle adaptation in

Rooksana E Noorai, Stevin Wilson, Lesly A Temesvari

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rooksana E NooraiClemson University Genomics and Bioinformatics Facility (CUGBF), Clemson, SC 29634.ORCID 0000-0002-9992-5198
Stevin WilsonClemson University Genomics and Bioinformatics Facility (CUGBF), Clemson, SC 29634.ORCID 0000-0002-9662-5501
Lesly A TemesvariDepartment of Biological Sciences, Clemson University, Clemson, SC 29634.ORCID 0000-0002-4154-8158

Funding

Regulation of Cryptosporidium DevelopmentP20GM146584 · NIGMS · CLEMSON UNIVERSITY · PI Katelyn Ann Walzer · 2022 to 2026
$13.5M
The role of acetate fermentation in Entamoeba histolytica growth and infectionP20GM109094 · NIGMS · CLEMSON UNIVERSITY · PI KOZUBOWSKI, LUKASZ · 2016 to 2020
$10.4M
NIGMS NIH HHS P20 GM109094NIGMS NIH HHS P20 GM146584
6 · The paper itself

Abstract

Intrinsic protein disorder plays a central role in cellular regulation and host-pathogen interactions, yet its proteome-wide distribution and functional organization in amoebozoan parasites remain poorly understood. Here, we present the first comparative analysis of intrinsic disorder across the proteomes of

Identifiers

PMID42845589
PMCPMC13640752

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.