Evidence map›Paper›PMID 42845556›Full record

ArticleResearch square2026

One Health tick bite exposure biomarkers against Ixodes ricinus salivary peptides.

Alexis Dziedziech, Bruno Passet, Alice Raffetin, Anavaj Sakuntabhai, Richard Paul, Kristina Persson, Sarah I Bonnet

Abstract readPreprint
In one paragraph

Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alexis DziedziechLund University.ORCID 0000-0001-7647-7639
Bruno PassetInstitut Pasteur.
Alice RaffetinIntercommunal Hospital of Villeneuve-Saint-Georges.
Anavaj SakuntabhaiInstitut Pasteur - Functional Genetics of Infectious Diseases Unit.ORCID 0000-0001-9099-6937
Richard PaulInstitut Pasteur.
Sarah I BonnetInstitut Pasteur.

Funding

Inter-regional study of transmission, adaptation and pathogenesis of viruses with pandemic potential in Southeast Asia and West/Central AfricaU01AI151758 · NIAID · INSTITUT PASTEUR · PI SAKUNTABHAI, ANAVAJ, SIMON-LORIERE, ETIENNE · 2020 to 2024
$6.7M
NIAID NIH HHS U01 AI151758
6 · The paper itself

Abstract

The changing distributions and activity patterns of tick populations underscore the urgent need for enhanced surveillance and risk assessment strategies for ticks and tick-borne diseases (TBDs) affecting humans and animals. Biomarkers of exposure to tick salivary peptides can be used to identify tick bite history and to monitor tick species distributions. Here, we derived peptides from previously identified immunogenic proteins, namely IrCalreticulin, IrLip1, and IrSPI. Bioinformatic predictive analysis of 3D structure and computed docking strength were used to identify candidate peptides based on predicted immunogenicity and arthropod homology. Using ELISA, several peptides distinguished sera from experimentally

Indexed as

BiomarkerDiagnosticsIxodes ricinusSurveillanceTick exposureTicks

Identifiers

PMID42845556
PMCPMC13640923

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.