Evidence map›Paper›PMID 42845497›Full record

ArticlebioRxiv : the preprint server for biology2026

Mechanistic insights into redox activity and catalytic determinants of the haloarchaeal flavin-dependent oxidoreductase

Katherine R Weber, Peter Huynh, Brianna Novillo, Semaj Bulter-Drinks, Christian Heryakusuma, Biswarup Mukhopadhyay, Endang Purwantini, Julie A Maupin-Furlow

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Katherine R WeberDepartment of Microbiology and Cell Science, Institute of Food and Agricultural Science, University of Florida, Gainesville, FL, USA.
Peter HuynhDepartment of Microbiology and Cell Science, Institute of Food and Agricultural Science, University of Florida, Gainesville, FL, USA.
Brianna NovilloDepartment of Microbiology and Cell Science, Institute of Food and Agricultural Science, University of Florida, Gainesville, FL, USA.
Semaj Bulter-DrinksDepartment of Microbiology and Cell Science, Institute of Food and Agricultural Science, University of Florida, Gainesville, FL, USA.
Christian HeryakusumaDepartment of Biochemistry, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA.
Biswarup MukhopadhyayDepartment of Biochemistry, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA.
Endang PurwantiniDepartment of Biochemistry, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA.
Julie A Maupin-FurlowDepartment of Microbiology and Cell Science, Institute of Food and Agricultural Science, University of Florida, Gainesville, FL, USA.ORCID 0000-0001-6105-0923

Funding

Interplay between post-translational modification systems in ArchaeaR35GM161171 · NIGMS · UNIVERSITY OF FLORIDA · PI JULIE A MAUPIN-FURLOW · 2026 to 2026
$384k
NIGMS NIH HHS R35 GM161171
6 · The paper itself

Abstract

Members of the FAD-dependent oxidoreductase family (IPR050260) play diverse and key roles in maintaining cellular redox balance, yet the functions of many distinct subgroups within this family remain unknown. Here, we define the biochemical and physiological functions of the

Indexed as

electron transferFAD bindingFerredoxin reductaseflavoenzymeHaloferax volcaniihalophilic archaeaNAD(P)H oxidaseredox biochemistry

Identifiers

PMID42845497
PMCPMC13640641

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.