Evidence map›Paper›PMID 42845466›Full record

ArticlebioRxiv : the preprint server for biology2026

Analysis of the DNA-binding domain of the

Zichu Yang, Anvita Billa, Aditya S Desai, Matthew R Parsek, Ajai A Dandekar

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zichu YangDepartment of Microbiology, University of Washington, Seattle, WA 98195.
Anvita BillaDepartment of Microbiology, University of Washington, Seattle, WA 98195.
Aditya S DesaiDepartment of Medicine, University of Washington, Seattle, WA 98195.
Matthew R ParsekDepartment of Microbiology, University of Washington, Seattle, WA 98195.ORCID 0000-0003-2932-7966
Ajai A DandekarDepartment of Microbiology, University of Washington, Seattle, WA 98195.ORCID 0000-0002-2992-6523

Funding

The pel exopolysaccharide gene cluster of Pseudomonas aeruginosaR01AI077628 · NIAID · UNIVERSITY OF WASHINGTON · PI MATTHEW R. PARSEK, Daniel J Wozniak · 2009 to 2026
$7.1M
Molecular determinants and functions of bacterial polysaccharide cellular localizationR01AI183692 · NIAID · UNIVERSITY OF WASHINGTON · PI Patricia Lynne Howell, MATTHEW R. PARSEK · 2025 to 2026
$1.5M
Pseudomonas aeruginosa sociomicrobiologyR35GM152107 · NIGMS · UNIVERSITY OF WASHINGTON · PI Ajai Dandekar · 2024 to 2026
$1.2M
NIAID NIH HHS R01 AI077628NIAID NIH HHS R01 AI183692NIGMS NIH HHS R35 GM152107
6 · The paper itself

Abstract

Many bacteria engage in quorum sensing (QS), a cell-cell communication system used to coordinate group behaviors. In one type of QS, acyl-homoserine lactone signals generated by LuxI homologs bind to LuxR homolog transcription factors, usually resulting in gene activation. The genome of

Indexed as

AHLLuxRregulontranscription factor

Identifiers

PMID42845466
PMCPMC13640746

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.