Evidence map›Paper›PMID 42845403›Full record

ArticlebioRxiv : the preprint server for biology2026

The chromatin reader protein MLLT1 is critical to maintain normal B lymphopoiesis.

Janani Prakash, Nicholas J Achille, Emmalee R Adelman, Shubin Zhang, John H Bushweller, Maria E Figueroa, Charles S Hemenway, Nancy J Zeleznik-Le

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Janani PrakashIntegrative Cell Biology Program, Loyola University Chicago, Maywood, IL 60153.
Nicholas J AchilleDepartment of Cancer Biology, Loyola University Chicago, Maywood, IL 60153.
Emmalee R AdelmanDepartment of Biochemistry, University of Miami Miller School of Medicine, Miami, FL, 33136.ORCID 0000-0003-3429-0803
Shubin ZhangDepartment of Cancer Biology, Loyola University Chicago, Maywood, IL 60153.
John H BushwellerDepartment of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA 22903.ORCID 0000-0002-5386-1758
Maria E FigueroaDepartment of Biochemistry, University of Miami Miller School of Medicine, Miami, FL, 33136.
Charles S HemenwayDepartment of Pediatrics, Louisiana State University Health Sciences Center.ORCID 0000-0003-0562-9273
Nancy J Zeleznik-LeDepartment of Cancer Biology, Loyola University Chicago, Maywood, IL 60153.ORCID 0009-0005-2432-9892

Funding

AF9(MLLT3) Function in Leukemia and Normal HematopoiesisR01CA233749 · NCI · UNIVERSITY OF VIRGINIA · PI BUSHWELLER, JOHN HACKETT, FIGUEROA, MARIA EUGENIA · 2019 to 2023
$3.2M
NCI NIH HHS R01 CA233749
6 · The paper itself

Abstract

MLLT1 (also named ENL) is a chromatin reader protein whose encoding gene was originally identified as a chromosomal translocation partner with

Identifiers

PMID42845403
PMCPMC13640573

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.