Evidence map›Paper›PMID 42845229›Full record

ArticleAllergy, asthma & immunology research2026

Atopic Dermatitis and Sleep Disorders.

Genlong Bai, Xinyi Shao, Yi Ou, Jin Chen, Zhaofu Tan, Aijun Chen, Jingbo Zhang

Abstract read
In one paragraph

Article in Allergy, asthma & immunology research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Genlong BaiDepartment of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.ORCID https://orcid.org/0000-0002-3256-9504
Xinyi ShaoDepartment of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.ORCID https://orcid.org/0000-0001-7780-139X
Yi OuDepartment of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.ORCID https://orcid.org/0009-0008-4923-7814
Jin ChenDepartment of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.ORCID https://orcid.org/0000-0002-4373-1618
Zhaofu TanDepartment of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. casementtan@outlook.com.ORCID https://orcid.org/0009-0003-4231-4454
Aijun ChenDepartment of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. chenaijun@hospital.cqmu.edu.cn.ORCID https://orcid.org/0000-0002-3066-556X
Jingbo ZhangDepartment of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. 49554556samael@gmail.com.ORCID https://orcid.org/0000-0002-9426-209X

Funding

China Postdoctoral Science Foundation 2024M763893Outstanding Youth Foundation of Chongqing Province CSTB2024YCJH-KYXM0101The Chongqing Science and Technology Commission 2023NSCQ-MSX0321The First Clinical College Clinical Medicine first-class discipline construction project CYYY-BSYJSCXXM-202333The First Clinical College of Chongqing Medical University CYYY-BSYJSKYCXXM202428
6 · The paper itself

Abstract

purposeAtopic dermatitis (AD) is a common inflammatory skin disease affecting 129 million people worldwide and is characterized by recurrent eczema, severe pruritus, and skin barrier damage. Previous studies on AD-sleep disorder associations were limited by small sample sizes or single-center designs, lacking large-scale epidemiological evidence. This study aimed to investigate the association between AD and sleep disorders using the UK Biobank prospective cohort and to explore effects of sex, race, and obesity on this relationship.

methodsA prospective cohort design was employed, including 329,796 participants for cross-sectional analysis and 330,875 for longitudinal analysis. Multivariable logistic regression and Cox proportional hazards models were used. Subgroup and sensitivity analyses were performed to validate robustness.

resultsCross-sectional analysis showed that AD was significantly associated with increased sleep disorder risk (adjusted odds ratio, 2.84; 95% confidence interval [CI], 2.54-3.18;

conclusionsAD is an independent risk factor for sleep disorders, particularly in women and individuals with moderate BMI. Future research should further explore precision-targeted therapies and management strategies for specific populations.

Indexed as

Atopic dermatitiscohort studyeczemaobesitypruritusskinsleep disordersUK Biobank

Identifiers

PMID42845229
PMCPMC13655399

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.