ArticleAllergy, asthma & immunology research2026
Association Between C-Reactive Protein-Triglyceride Glucose Index and All-Cause Mortality and Exacerbation in Adult Asthma: NHANES, 1999-2010 and 2015-2018.
Article in Allergy, asthma & immunology research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study investigates the association between the C-reactive protein-triglyceride-glucose index (CTI), indicative of systemic inflammation and insulin resistance, and all-cause mortality as well as asthma exacerbations in adults with asthma.
methodsData from eight cycles of the US National Health and Nutrition Examination Survey (1999-2010 and 2015-2018) were analyzed. Adults aged ≥ 20 years were included, excluding those who were missing key variables. This resulted in 13,972 participants, of whom 1,832 had asthma. Participants were grouped into CTI tertiles. Participants self-reported exacerbations, and survival status was linked with the National Death Index. Complex survey weighting was applied to ensure national representativeness. Weighted multivariate logistic regression and Cox proportional hazards models assessed associations while adjusting for demographics, socioeconomic factors, body mass index, smoking, alcohol consumption, comorbidities, and laboratory indicators.
resultsThe fully adjusted model revealed no significant association between CTI and asthma prevalence (odds ratio [OR], 1.07; 95% confidence interval [CI], 0.99-1.16;
conclusionsIn this nationally representative sample, higher CTI was associated with higher all-cause mortality and higher odds of recent asthma exacerbations among adults with asthma, while no significant association with asthma prevalence was observed. CTI may help inform prognostic stratification in asthma and prospective studies are warranted.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.