Evidence map›Paper›PMID 42845207›Full record

ArticleAnnals of dermatology2026

Antibacterial, Anti-Inflammatory and Anti-Melanogenic Effects of a Novel Peptide.

Mina Song, Jeong Hyeon Lee, Si-Eun Park, Jung Im Lee, Youngsup Song, Sung Eun Chang

Abstract read
In one paragraph

Article in Annals of dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mina Song *Department of Dermatology, Brain Korea 21 Project, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0009-0003-5200-9189
Jeong Hyeon Lee *Department of Dermatology, Brain Korea 21 Project, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-5160-1760
Si-Eun ParkDepartment of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0009-0000-7484-8395
Jung Im LeeDermafirm Inc., Derma Science Lab, Ltd., Seoul, Korea.ORCID https://orcid.org/0009-0007-2297-0859
Youngsup SongDepartment of Brain Sciences, Brain Korea 21 Project, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. ysong@amc.seoul.kr.ORCID https://orcid.org/0000-0002-6268-5223
Sung Eun ChangDepartment of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. cse@amc.seoul.kr.ORCID https://orcid.org/0000-0003-4225-0414

Funding

Dermafirm INC, Republic of Korea 2023-0873Korea Health Industry Development Institute RS-2023-KH140998
6 · The paper itself

Abstract

backgroundAcne-induced post-inflammatory hyperpigmentation (PIH) is driven by

objectiveThis study aimed to evaluate the anti-bacterial, anti-inflammatory, and anti-melanogenic effects of a newly made 2-isopropyl-5-methylphenol-conjugated valine-tryptophan dipeptide (2IP5MP-VW).

methodsIPMP-VW conjugates were synthesized and screened for antibacterial activity against

resultsAmong the synthesized candidates, 2IP5MP-VW showed the strongest antibacterial activity against

conclusion2IP5MP-VW exhibits multifunctional anti-bacterial, anti-inflammatory, and anti-melanogenic activities, suggesting its potential as a candidate for the management of acne-induced PIH.

Indexed as

AcnePeptidePost-inflammatory hyperpigmentation

Identifiers

PMID42845207
PMCPMC13655619

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.