Evidence map›Paper›PMID 42845204›Full record

ArticleAnnals of dermatology2026

Efficacy of Calcipotriol/Betamethasone Ointment in the Management of Pediatric Alopecia Areata.

Yumi Won, Jungsoo Lee, Hoonsoo Kim, Hyunchang Ko, Byungsoo Kim, Moon-Bum Kim

Abstract read
In one paragraph

Article in Annals of dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yumi WonDepartment of Dermatology, School of Medicine, Pusan National University, Busan, Korea.ORCID https://orcid.org/0000-0003-3172-9913
Jungsoo LeeDepartment of Dermatology, School of Medicine, Pusan National University, Busan, Korea.ORCID https://orcid.org/0000-0002-7519-8192
Hoonsoo KimDepartment of Dermatology, School of Medicine, Pusan National University, Busan, Korea.ORCID https://orcid.org/0000-0002-7649-1446
Hyunchang KoDepartment of Dermatology, School of Medicine, Pusan National University, Busan, Korea.ORCID https://orcid.org/0000-0002-3459-5474
Byungsoo KimDepartment of Dermatology, School of Medicine, Pusan National University, Busan, Korea.ORCID https://orcid.org/0000-0003-0054-8570
Moon-Bum KimDepartment of Dermatology, School of Medicine, Pusan National University, Busan, Korea.ORCID https://orcid.org/0000-0003-4837-0214

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTopical corticosteroids are acknowledged as the first-line treatment for pediatric alopecia areata. There are cases that are recalcitrant to topical corticosteroid application.

objectiveThe objective was to evaluate the efficacy of calcipotriol/betamethasone ointment in pediatric alopecia areata.

methodsIn a 12-week retrospective study, 40 patients under 10 years old with alopecia areata were included. The patients were treated with a topical ointment combining 0.005% calcipotriol and betamethasone dipropionate once daily. The efficacy was monitored through changes in Severity of Alopecia Tool (SALT) scores.

resultsThe 40 patients, with a mean age of 4.1±2.1 years, were categorized by their SALT scores into two groups: those above and below 50. Patients with SALT scores over 50 showed hair regrowth in 7.44±4.44 weeks, while those with SALT scores under 50 showed regrowth in 5.71±2.58 weeks. After 12 weeks, 80.0% of the patients showed hair regrowth and 20.0% of patients showed no response or worsening. Only minor adverse events were documented during follow-up.

conclusionCalcipotriol/betamethasone ointment may represent a useful topical option for pediatric alopecia areata.

Indexed as

AlopeciaAlopecia areataBetamethasoneCalcipotriolChild

Identifiers

PMID42845204
PMCPMC13655622

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.