Evidence map›Paper›PMID 42844473›Full record

ArticleNature2026

A gut microbial odd-chain fatty acid alleviates atherosclerosis in mice.

Chao Yin, Youzhe Chen, Gan Lin, Mingwei Cai, Cuiping Pang, Xianzun Xiao, Kaining Han, Chaoxiong Mei, Miaomiao Qin, Peizhi Fan and 19 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Chao Yin *Shenzhen Key Laboratory for Systems Medicine in Inflammatory Diseases, Zhongshan School of Medicine, Shenzhen Campus of Sun Yat-sen University, Shenzhen, China.
Youzhe Chen *Institute of Chemical Biology, Shenzhen Bay Laboratory, Shenzhen, China.
Gan Lin *Shenzhen Key Laboratory for Systems Medicine in Inflammatory Diseases, Zhongshan School of Medicine, Shenzhen Campus of Sun Yat-sen University, Shenzhen, China.ORCID http://orcid.org/0009-0003-7492-0141
Mingwei Cai *Institute of Chemical Biology, Shenzhen Bay Laboratory, Shenzhen, China.ORCID http://orcid.org/0000-0002-2757-6742
Cuiping PangCAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Xianzun XiaoShenzhen Key Laboratory for Systems Medicine in Inflammatory Diseases, Zhongshan School of Medicine, Shenzhen Campus of Sun Yat-sen University, Shenzhen, China.
Kaining HanShenzhen Key Laboratory for Systems Medicine in Inflammatory Diseases, Zhongshan School of Medicine, Shenzhen Campus of Sun Yat-sen University, Shenzhen, China.
Chaoxiong MeiShenzhen Key Laboratory for Systems Medicine in Inflammatory Diseases, Zhongshan School of Medicine, Shenzhen Campus of Sun Yat-sen University, Shenzhen, China.
Miaomiao QinInstitute of Chemical Biology, Shenzhen Bay Laboratory, Shenzhen, China.
Peizhi FanShenzhen Key Laboratory for Systems Medicine in Inflammatory Diseases, Zhongshan School of Medicine, Shenzhen Campus of Sun Yat-sen University, Shenzhen, China.
Yibo ZhaoShenzhen Key Laboratory for Systems Medicine in Inflammatory Diseases, Zhongshan School of Medicine, Shenzhen Campus of Sun Yat-sen University, Shenzhen, China.
Lihong DuShenzhen Key Laboratory for Systems Medicine in Inflammatory Diseases, Zhongshan School of Medicine, Shenzhen Campus of Sun Yat-sen University, Shenzhen, China.
Yanqin XieShenzhen Key Laboratory for Systems Medicine in Inflammatory Diseases, Zhongshan School of Medicine, Shenzhen Campus of Sun Yat-sen University, Shenzhen, China.
Jiang WangInstitute of Chemical Biology, Shenzhen Bay Laboratory, Shenzhen, China.
Yudan MaoShenzhen Key Laboratory for Systems Medicine in Inflammatory Diseases, Zhongshan School of Medicine, Shenzhen Campus of Sun Yat-sen University, Shenzhen, China.
Xiangting ZhouShenzhen Key Laboratory for Systems Medicine in Inflammatory Diseases, Zhongshan School of Medicine, Shenzhen Campus of Sun Yat-sen University, Shenzhen, China.
Xue GaoShenzhen Key Laboratory for Systems Medicine in Inflammatory Diseases, Zhongshan School of Medicine, Shenzhen Campus of Sun Yat-sen University, Shenzhen, China.
Li JinShenzhen Key Laboratory for Systems Medicine in Inflammatory Diseases, Zhongshan School of Medicine, Shenzhen Campus of Sun Yat-sen University, Shenzhen, China.
Peijie LiShenzhen Key Laboratory for Systems Medicine in Inflammatory Diseases, Zhongshan School of Medicine, Shenzhen Campus of Sun Yat-sen University, Shenzhen, China.
Zepeng QuCAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.ORCID http://orcid.org/0009-0003-2443-5383
Zhipeng TanDepartment of Clinical Laboratory, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, China.
Ruolan SunInstitute of Chemical Biology, Shenzhen Bay Laboratory, Shenzhen, China.
Xiahong LinDepartment of Geriatrics, Shenzhen Key Laboratory of Bone Tissue Repair and Translational Research, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.
Yang ZhangShenzhen Medical Academy of Research and Translation (SMART), Shenzhen, China.ORCID http://orcid.org/0000-0003-3625-9965
Lei DaiCAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.ORCID http://orcid.org/0000-0002-5598-5308
Zhaofan LuoDepartment of Clinical Laboratory, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, China.
Xiangyu MouShenzhen Key Laboratory for Systems Medicine in Inflammatory Diseases, Zhongshan School of Medicine, Shenzhen Campus of Sun Yat-sen University, Shenzhen, China. mouxy5@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0002-6227-6315
Xiaoyu TangInstitute of Chemical Biology, Shenzhen Bay Laboratory, Shenzhen, China. xtang@microbechembio.org.ORCID http://orcid.org/0000-0002-6406-9870
Wenjing ZhaoShenzhen Key Laboratory for Systems Medicine in Inflammatory Diseases, Zhongshan School of Medicine, Shenzhen Campus of Sun Yat-sen University, Shenzhen, China. Zhaowj29@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0003-1706-6324

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut microbiota plays a pivotal part in human health, yet the molecular mechanisms that underlie its effects are largely unexplored. Bacteroides, a dominant genus in the human gut microbiota, is depleted in patients with atherosclerosis

Identifiers

PMID42844473

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.