Evidence map›Paper›PMID 42844467›Full record

ArticleNature2026

Dynamics of human cardiogenesis and its disruption in trisomy 21.

James Cranley, Kazumasa Kanemaru, Semih Bayraktar, Vincent Knight-Schrijver, Rebecca Hulbert, Eva Lana-Elola, Rifdat Aoidi, Jan Patrick Pett, Anna Wilbrey-Clark, Krzysztof Polanski and 27 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors.

James Cranley *Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-0408-5801
Kazumasa Kanemaru *Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK. kk837@cam.ac.uk.
Semih Bayraktar *Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0001-9549-7117
Vincent Knight-SchrijverCambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-7916-3827
Rebecca HulbertThe Francis Crick Institute, London, UK.ORCID http://orcid.org/0009-0000-7852-8268
Eva Lana-ElolaThe Francis Crick Institute, London, UK.
Rifdat AoidiThe Francis Crick Institute, London, UK.
Jan Patrick PettWellcome Sanger Institute, Hinxton, UK.ORCID http://orcid.org/0000-0002-5249-444X
Anna Wilbrey-ClarkCambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.
Krzysztof PolanskiCambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-2586-9576
Monika DabrowskaWellcome Sanger Institute, Hinxton, UK.
Ilaria MulasWellcome Sanger Institute, Hinxton, UK.ORCID http://orcid.org/0000-0003-2556-9685
Harriet JohnsonWellcome Sanger Institute, Hinxton, UK.ORCID http://orcid.org/0000-0003-0075-5297
Noemie CombemorelCambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.
Yizhou YuCambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-4800-9392
Jack A PalmerCambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.
Woochan LeeCambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.
Jore Van WauweCambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0003-2969-1805
John-Poul Ng-BlichfeldtCambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.
Laura RichardsonWellcome Sanger Institute, Hinxton, UK.ORCID http://orcid.org/0000-0002-8075-3816
Claudia I SemprichCambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-2446-9028
Rakeshlal KapugeCambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.
Shani PereraCambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.
Xiaoling HeJohn van Geest Centre for Brain Repair, Cambridge University, Cambridge, UK.ORCID http://orcid.org/0009-0004-1002-8418
Siew Yen HoCardiac Morphology Unit, Royal Brompton Hospital and Imperial College London, London, UK.ORCID http://orcid.org/0000-0002-3913-5637
Nadav YayonCambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-7034-0524
Liz TuckWellcome Sanger Institute, Hinxton, UK.ORCID http://orcid.org/0000-0002-1837-7549
Kenny RobertsWellcome Sanger Institute, Hinxton, UK.ORCID http://orcid.org/0000-0001-6155-0821
Hongorzul DavaapilCambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.
Laure GambardellaCambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0001-5771-1565
Anna PhilpottCambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0003-3789-2463
Minal PatelWellcome Sanger Institute, Hinxton, UK.
Richard C V TyserCambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0001-7884-1756
Andreia Sofia BernardoThe Francis Crick Institute, London, UK.
Victor L J TybulewiczThe Francis Crick Institute, London, UK.ORCID http://orcid.org/0000-0003-2439-0798
Sanjay SinhaCambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK. ss661@cam.ac.uk.ORCID http://orcid.org/0000-0001-5900-1209
Sarah A TeichmannCambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK. sat1003@cam.ac.uk.ORCID http://orcid.org/0000-0002-6294-6366

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Developmental dynamics involve the specification of diverse cell types and their spatial organization into multicellular niches

Identifiers

PMID42844467

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.