Evidence map›Paper›PMID 42844384›Full record

ArticleAesthetic plastic surgery2026

Redefining the Facial Artery Safe Zone: A Dynamic, Segment-Based Vascular Risk Analysis.

Emre Kaygin, Tuncay Colak, Ozgur Cakir

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Article in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Emre KayginDepartment of Anatomy, Faculty of Medicine, Kocaeli University, İzmit, Kocaeli, Turkey. emre.kaygin@kocaeli.edu.tr.ORCID http://orcid.org/0000-0003-3704-0033
Tuncay ColakDepartment of Anatomy, Faculty of Medicine, Kocaeli University, İzmit, Kocaeli, Turkey.ORCID http://orcid.org/0000-0002-9483-3243
Ozgur CakirDepartment of Radiology, Faculty of Medicine, Kocaeli University, İzmit, Kocaeli, Turkey.ORCID http://orcid.org/0000-0001-6565-9488

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe growing number of facial esthetic procedures has heightened the importance of understanding the anatomy, variations, and potential complications associated with the facial artery, the principal arterial supply of the face. This study aims to characterize the topographic and morphometric features of the facial artery and to examine age- and sex-related anatomical variations that may have implications for facial esthetic procedures. MATERIALS AND

methodsTen facial arteries were examined in six cadavers, and a total of 300 facial arteries were examined in 150 individuals (75 women and 75 men) using three-dimensional computed tomography angiography (3D-CTA). In addition to the 10 morphometric parameters determined, facial arteries were evaluated in terms of age and sex, branching pattern, termination type, and anastomotic structure.

resultsThe most common termination types were Type 2 (32%) and Type 1 (22%). The columellar branch was found in 74% of cases. Sex-based analyses showed that the artery ran significantly more laterally in men in the mandibular and perioral segments, and in women in the nasal segment (p < 0.05). Age-related analyses identified modest positional differences, with a tendency toward a relatively more superomedial position of the facial artery and closer proximity to the orbital region and medial canthus in older individuals.

conclusionOur findings suggest that the concept of a universally applicable facial artery "safe zone" may not fully account for individual anatomical variability. These anatomical findings may contribute to individualized anatomical assessment and procedural planning during facial esthetic procedures. NO LEVEL ASSIGNED: This journal requires that authors assign a level of evidence to each submission to which Evidence-Based Medicine rankings are applicable. This excludes Review Articles, Book Reviews, and manuscripts that concern Basic Science, Animal Studies, Cadaver Studies, and Experimental Studies. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Indexed as

Anatomical variationDermal fillersFacial arteryFacial artery branching patternInjection safetyVascular complications

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.