Evidence map›Paper›PMID 42843846›Full record

SynthesisEuropean respiratory review : an official journal of the European Respiratory Society2026

Manual compared to automated closed-loop oxygen control strategies in hospitalised adults: a systematic review and meta-analysis.

Louis Kirton, Rowan Biggs, Neakiry Kivi, Francesca Lynch, Tanira Kingi, Ross Sayers, Jenny Sparks, Allie Eathorne, Mark Weatherall, Richard Beasley

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in European respiratory review : an official journal of the European Respiratory Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Louis KirtonThe Medical Research Institute of New Zealand, Wellington, New Zealand louis.kirton@mrinz.ac.nz.ORCID https://orcid.org/0000-0001-6941-1615
Rowan BiggsThe Medical Research Institute of New Zealand, Wellington, New Zealand.ORCID https://orcid.org/0009-0000-1385-1064
Neakiry KiviThe Medical Research Institute of New Zealand, Wellington, New Zealand.
Francesca LynchThe Medical Research Institute of New Zealand, Wellington, New Zealand.
Tanira KingiThe Medical Research Institute of New Zealand, Wellington, New Zealand.
Ross SayersThe Medical Research Institute of New Zealand, Wellington, New Zealand.ORCID https://orcid.org/0000-0001-8780-9109
Jenny SparksThe Medical Research Institute of New Zealand, Wellington, New Zealand.
Allie EathorneThe Medical Research Institute of New Zealand, Wellington, New Zealand.
Mark WeatherallUniversity of Otago Wellington, Wellington, New Zealand.
Richard BeasleyThe Medical Research Institute of New Zealand, Wellington, New Zealand.ORCID https://orcid.org/0000-0003-0337-406X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClosed-loop oxygen control (CLOC) systems improve accuracy of oxygen delivery compared with standard manual oxygen adjustment. Determination of their efficacy in delivering oxygen noninvasively to adults, using different delivery methods and across different hospital locations, would enhance clinical practice.

methodsWe conducted a systematic review and meta-analysis, searching Medline, Embase, Scopus Basic and Advanced, and Cochrane databases. Randomised controlled trials comparing time spent within a target peripheral oxygen saturation (

resultsThe search identified 3777 papers; of these, seven were included, with 635 participants. The mean proportion of time spent within the target

conclusionsCLOC improves adherence to a target

Indexed as

HospitalizationOxygenOxygen Inhalation TherapyAdultAutomationHumansOxygen SaturationTime FactorsTreatment OutcomeOxygen

Identifiers

PMID42843846
PMCPMC13643497

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.