Evidence map›Paper›PMID 42842779›Full record

ArticleThe neuroradiology journal2026

Radiological DESH score cannot predict outcome after shunt surgery: A Swedish prospective follow-up study.

Clara Constantinescu, Mia Emgård, Karin Sundström, Dan Farahmand, Mats Tullberg, Doerthe Ziegelitz, Per Hellström

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Article in The neuroradiology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Clara ConstantinescuHydrocephalus Research Unit, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0003-1830-1699
Mia EmgårdDepartment of Radiology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0009-0006-1223-7234
Karin SundströmDepartment of Radiology, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden.
Dan FarahmandHydrocephalus Research Unit, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Mats TullbergHydrocephalus Research Unit, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Doerthe ZiegelitzHydrocephalus Research Unit, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0002-6769-3150
Per HellströmHydrocephalus Research Unit, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0001-9803-7271

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundDisproportionately enlarged subarachnoid-space hydrocephalus (DESH) has been proposed as a radiological predictor of shunt responsiveness in idiopathic normal pressure hydrocephalus (iNPH), but previous studies have reported inconsistent results. We investigated the association between preoperative DESH score and postoperative outcome after shunt surgery in a prospective iNPH cohort.MethodsThis prospective study included 101 consecutive patients with iNPH from the Gothenburg Prediction of Outcome in iNPH (POiNT) study. Preoperative DESH scores were assessed on MRI using previously published criteria. Clinical outcomes included the Gothenburg iNPH scale, modified Rankin Scale (mRS), Mini-Mental State Examination (MMSE), and Timed Up and Go test (TUG-t). The primary outcome was improvement of ≥5 points on the iNPH scale.ResultsMean preoperative DESH score was 6.3 ± 1.7. At follow-up, the mean iNPH scale score improved from 50.8 ± 19.8 to 63.3 ± 20.0 (

Indexed as

DESH scoredisproportionately enlarged subarachnoid-space hydrocephalusidiopathic normal pressure hydrocephalusimaging markersMRI

Identifiers

PMID42842779
PMCPMC13646207

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