Evidence map›Paper›PMID 42842650›Full record

ArticleScience advances2026

Epigenetic insights into extreme longevity in the world's oldest terrestrial animal, Jonathan.

Benjamin Vaisvil, Daniel P Schmitt, Angela Jones, Vinayak Kapatral, James M Ford, Madison L Taylor, Mathia Colwell, Jonathan Hollins, Sam Pascucci, Konstantin Weissenow and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Benjamin VaisvilKallel Foundation, Nashville, TN, USA.ORCID 0000-0003-1688-0295
Daniel P SchmittIgenbio, Inc., Chicago, IL, USA.ORCID 0009-0002-6057-5669
Angela JonesVANTAGE, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0002-1565-4360
Vinayak KapatralIgenbio, Inc., Chicago, IL, USA.
James M FordVanderbilt University, Nashville, TN, USA.
Madison L TaylorVANTAGE, Vanderbilt University Medical Center, Nashville, TN, USA.
Mathia ColwellOregon Institute of Occupational Health Sciences, Oregon Health and Science University, Portland, OR, USA.ORCID 0000-0001-5008-8520
Jonathan HollinsAgriculture and Natural Resources Division, St. Helena Government, Jamestown, St. Helena.ORCID 0009-0005-8290-0903
Sam PascucciFlorida Iguana & Tortoise Breeders, Southwest Ranches, FL, USA.
Konstantin WeissenowDepartment of Bioinformatics & Computational Biology, Technical University of Munich, Munich, Germany.ORCID 0000-0002-2205-1795
Burkhard RostDepartment of Bioinformatics & Computational Biology, Technical University of Munich, Munich, Germany.ORCID 0000-0003-0179-8424
Pascal NotinSystems Biology Department, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-1877-8983
Justin GerlachPeterhouse, University of Cambridge, Cambridge, UK.ORCID 0000-0002-0157-0449
Thomas C TerwilligerNew Mexico Consortium, Los Alamos, NM, USA.ORCID 0000-0001-6384-0320
Li-Wei HungLos Alamos National Laboratory, Los Alamos, NM, USA.ORCID 0000-0001-6690-8458
Lars Juhl JensenNNF Center for Protein Research, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-7885-715X
Kathlyn ReedSeaWorld of Texas, San Antonio, TX, USA.
Todd R RobeckUnited Parks and Resorts, Orlando, FL, USA.ORCID 0000-0001-8573-5070
Steve HorvathThe University of California, Los Angeles, Los Angeles, CA, USA.ORCID 0000-0002-4110-3589
Christopher FaulkDepartment of Animal Science, University of Minnesota, Minneapolis, MN, USA.ORCID 0000-0002-9749-9658
Yanjun MaTennessee Oncology, Nashville, TN, USA.ORCID 0009-0008-0494-4398
Stephen W ClarkKallel Foundation, Nashville, TN, USA.ORCID 0000-0003-1732-1065

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aldabra giant tortoises (

Indexed as

Epigenesis, GeneticLongevityTurtlesAgingAnimalsDNA MethylationMitochondriaPromoter Regions, Genetic

Identifiers

PMID42842650
PMCPMC13644754

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.