ArticleProceedings of the National Academy of Sciences of the United States of America2026
Diversity and spatial segregation of TRP channels in the closest relatives of animals.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
- Diversity and spatial segregation of TRP channels in the closest relatives of animals.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
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3 authors.
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Abstract
Sensory systems, built around specialized cell types, are central to how animals perceive and respond to their environments. However, the evolutionary origin of these systems remains unclear. Here, we show that choanoflagellates, the sister group of animals, possess remarkably diverse repertoires of transient receptor potential (TRP) channels, an ancient superfamily of sensory ion channels. Comparative analyses indicate that most major animal TRP channel families predate the origin of animals and reveal extensive radiations of the TRPM and TRPW families within choanoflagellates, with the latter family likely being lost in the animal lineage. Furthermore, in the choanoflagellate model
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