Evidence map›Paper›PMID 42842405›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Myeloid cell reprogramming drives enhanced defense against

Sara N Stoner, Eric D Larson, Sam Fulte, Steven C Shaw, Erin R Fish, Edward N Janoff, Matthias Mack, Sarah E Clark

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Myeloid cell reprogramming drives enhanced defense againstProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Sara N StonerDepartment of Otolaryngology-Head and Neck Surgery, University of Colorado School of Medicine, Aurora, CO 80045.ORCID 0000-0002-9350-9441
Eric D LarsonDepartment of Basic and Translational Sciences, University of Pennsylvania School of Dental Medicine, Philadelphia, PA 19104.
Sam FulteDepartment of Otolaryngology-Head and Neck Surgery, University of Colorado School of Medicine, Aurora, CO 80045.
Steven C ShawDepartment of Otolaryngology-Head and Neck Surgery, University of Colorado School of Medicine, Aurora, CO 80045.
Erin R FishDepartment of Otolaryngology-Head and Neck Surgery, University of Colorado School of Medicine, Aurora, CO 80045.
Edward N JanoffDivision of Infectious Diseases, University of Colorado School of Medicine, Aurora, CO 80045.ORCID 0000-0003-2702-5729
Matthias MackDepartment of Nephrology, University Hospital Regensburg, Regensburg 93053, Germany.
Sarah E ClarkDepartment of Otolaryngology-Head and Neck Surgery, University of Colorado School of Medicine, Aurora, CO 80045.ORCID 0000-0002-5975-5032

Funding

TRAINING PROGRAM IN IMMUNOLOGYT32AI007405 · NIAID · UNIVERSITY OF COLORADO DENVER · PI Laurel L Lenz, Raul Martin Torres · 1991 to 2026
$10.5M
Institutional Training in Otolaryngology ResearchT32DC012280 · NIDCD · UNIVERSITY OF COLORADO DENVER · PI Yuri Agrawal, Sue C. Kinnamon · 2013 to 2026
$3.4M
Airway Prevotella enhance innate immune-mediated protection against lung infectionR01AI172958 · NIAID · UNIVERSITY OF COLORADO DENVER · PI Sarah E Clark · 2023 to 2026
$2.0M
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI172958HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) T32AI007405HHS | NIH | National Institute on Deafness and Other Communication Disorders (NIDCD) T32DC012280NIAID NIH HHS R01 AI172958NIAID NIH HHS T32 AI007405NIDCD NIH HHS T32 DC012280
6 · The paper itself

Abstract

Clinical data link the prevalent respiratory tract anaerobe

Indexed as

Myeloid CellsPneumonia, PneumococcalPrevotellaStreptococcus pneumoniaeAnimalsLungMacrophagesMiceMice, Inbred C57BLNeutrophilsPhagocytosislung infectionlung microbiomePrevotellasingle cell RNA sequencingStreptococcus pneumoniae

Identifiers

PMID42842405
PMCPMC13663786

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.