ArticleEuropean geriatric medicine2026
Association between early in-hospital physiological and functional changes and fall risk in older adults: a retrospective multicenter cohort study.
Article in European geriatric medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo examine whether early in-hospital changes in functional status and selected physiological parameters were associated with subsequent falls among hospitalized older adults.
methodsThis retrospective multicenter cohort study used electronic health record and administrative data from two tertiary hospitals in Japan between 2018 and 2024. Patients aged 65 years or older underwent landmark assessments on hospital days 3 (LM3) and 7 (LM7). Functional trajectories were defined from changes in transfer ability between admission and each landmark; physiological changes included serum albumin, hemoglobin, and sodium. The outcome was the first documented in-hospital fall within 30 days after each landmark. Associations were estimated using multivariable logistic regression with multiple imputation.
resultsOf 112,103 eligible patients, 83,297 were included in LM3 and 61,071 in LM7. Patients ranged in age from 65 to 106 years in both cohorts; 40.6% of the LM3 cohort and 40.9% of the LM7 cohort were female. Persistent or worsening transfer impairment was associated with higher fall risk at both landmarks. Acute functional decline was associated with higher fall risk at LM7 but not LM3. Declines in hemoglobin and serum sodium were independently associated with higher fall risk in both analyses, whereas changes in serum albumin were not. Findings were consistent across sensitivity analyses.
conclusionFunctional and physiological changes during early hospitalization were associated with subsequent fall risk in older adults. Reassessment on hospital days 3 and 7 may complement admission-based assessment by identifying evolving vulnerability and supporting time-sensitive fall-prevention strategies.
Indexed as
Identifiers
42842205What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.